primary immune response


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im·mune re·sponse

1. any response of the immune system to an antigen including antibody production and/or cell-mediated immunity;
2. the response of the immune system to an antigen (immunogen) that leads to the condition of induced sensitivity; the immune response to the initial antigenic exposure (primary immune response) is detectable, as a rule, only after a lag period of from several days to 2 weeks; the immune response to a subsequent stimulus (secondary immune response) by the same antigen is more rapid than in the case of the primary immune response.
Farlex Partner Medical Dictionary © Farlex 2012

im·mune re·sponse

(i-myūn' rĕ-spons')
1. Any response of the immune system to an antigen including antibody production or cell-mediated immunity.
2. The response of the immune system to an antigen (immunogen) that leads to the condition of induced sensitivity; the immune response to the initial antigenic exposure (primary immune response) is detectable, as a rule, only after a lag period of from several days to 2 weeks; the immune response to a subsequent stimulus (secondary immune response) by the same antigen is more rapid than in the case of the primary immune response.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

primary immune response

The weak initial reaction caused by the first encounter of a ‘naive’ lymphocyte with a particular antigen. Antibodies are nor detectable for several days then rise to a (low) peak concentration and then fall again. If now there is a second challenge with the same antigen, there is a more rapid and much higher rise in the level of antibodies. This is the secondary immune response.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
When an animal receives the first injection of vaccine, the primary immune response takes place.
CD74 is an important piece of cellular machinery inside dendritic cells - which regulate mammalian primary immune responses.
Since the ability to mount primary immune responses relies on the availability of naive T cells, the circulating naive T-cell reservoir was evaluated throughout the human life span.

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