Research: In this trial, investigators set out to determine whether a ginkgo biloba-containing supplement could improve cognitive function and quality of life or alter primary hemostasis
. They also wanted to make sure it was safe in healthy, cognitively intact older adults.
(17) reported that ABS had in vivo hemostatic actions that may be therapeutic for the clinical management of patients with deficient primary hemostasis
. Furthermore, they reported that ABS exhibited a hemostatic effect via modulation of platelet functions.
PFA-100 (Platelet Function Analyzer) is a device that measures shear-induced, platelet-related primary hemostasis
in a citrated whole blood specimen.
The skin bleeding time (or alternative tests) and platelet aggregometry can be used to assess primary hemostasis
, but their results are not invariably correlated with clinical outcome in natural models of impaired primary hemostasis
Platelets are believed to play an important role in primary hemostasis
, wound healing, and re-epithelialization.
is the process involving vascular contraction and the accumulation of a platelet plug at the site of vascular injury.
Some of them improve primary hemostasis
, others stimulate fibrin formation or inhibit fibrinolysis.6 Some mechanisms are part of the preparation of a procoagulant substance in combination with a vehicle such as collagen matrix, whereas others use a matrix to provide a template for the endogenous coagulation cascade to achieve hemostasis.
A The Dade Behring PFA-100 platelet function analyzer is used to evaluate primary hemostasis
in citrated whole blood.
The diagnostic approach to abnormalities of primary hemostasis
is still a major challenge for clinical laboratories.
involves the adhesion of platelets to the injured vessels.
is a process whereby platelets interact with elements of the damaged vessel wall, leading to the initial formation of a "platelet plug[degrees].