Twenty-five patients with primary focal dystonia (15 patients with blepharospasm and 10 patients with cervical dystonia) (Table 1) were enrolled in the study from the outpatient clinic of movement disorders, Department of Neurology and Psychiatry, Sapienza, University of Rome.
Defazio et al., "Somatosensory temporal discrimination in patients with primary focal dystonia," Journal of Neurology, Neurosurgery, and Psychiatry, vol.
This study aimed to explore alterations in the basal ganglia in different forms of primary focal dystonia. Methods: cross-sectional observational study was performed between December 2013 and December 2014 in 80 patients with different forms of primary focal dystonia and 55 neurologically normal control subjects.
Previous studies on patients with primary focal dystonia utilizing TCS have shown a higher prevalence of LN hyperechogenicity in patients compared with controls,[sup],, which may be the result of moderate copper or manganese accumulation.[sup], The results of the present study regarding the prevalence of LN hyperechogenicity are consistent with these findings.
In conclusion, there is a greater prevalence of LN hyperechogenicity, as detected by TCS, in patients with primary focal dystonia than in neurologically normal populations.