Primary blast injury is thought to result from these blast wave-induced changes in atmospheric pressure, which is a form of barotrauma.
The vulnerability of the brain to secondary and tertiary blast injury is clear, but whether primary blast injury has direct effects on the brain remains unresolved.
Thus, in limited experimental studies, exposure of animals to primary blast injury suggests structural changes occur in the brain that can lead to neurological impairment.
Abbreviations: BCVA = best corrected visual acuity, COT = combat ocular trauma, DOD = Department of Defense, MEB = medical evaluation board, OEF = Operation Enduring Freedom, OIF = Operation Iraqi Freedom, PBI = primary blast injury, PNS = Polytrauma Network Site, PRC = Polytrauma Rehabilitation Center, QOL = quality of life, TBI = traumatic brain injury, VA = Department of Veterans Affairs, VFQ-25 = 25-Item Visual Functioning Questionnaire, WRAMC = Walter Reed Army Medical Center.
Primary blast injury (PBI) is caused by the blast wave itself with changes of atmospheric pressure.
Primary blast injury and basic research: A brief history.