primary aldosteronism


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Related to primary aldosteronism: secondary aldosteronism

aldosteronism

 [al-dos´ter-ōn-izm″, al″do-ster´ōn-izm]
an abnormality of electrolyte metabolism produced by excessive secretion of aldosterone, it may be primary or occur secondarily in response to extra-adrenal disease. There may be hypertension, hypokalemia, alkalosis, muscular weakness, polyuria, and polydipsia. Called also hyperaldosteronism.
primary aldosteronism that arising from oversecretion of aldosterone, characterized typically by hypokalemia, alkalosis, muscular weakness, polyuria, polydipsia, hypertension, cardiac irregularity, and tetany. The most common etiologic factors are adrenal adenoma, idiopathic hyperplasia of the adrenal cortex, and occasionally carcinoma of the adrenal gland. Most adenomas affect only one of the two glands and therefore can be removed surgically without depriving the patient of a sufficient supply of adrenal cortical hormones. If removal of both glands is necessary, this creates a serious and potentially fatal insufficiency of the hormones. Called also Conn's syndrome.
pseudoprimary aldosteronism that caused by bilateral adrenal hyperplasia and having the same signs and symptoms as primary aldosteronism.
secondary aldosteronism that due to extra-adrenal stimulation of aldosterone secretion; it is commonly associated with edematous states, as in nephrotic syndrome, hepatic cirrhosis, heart failure, and accelerated hypertension.

pri·mar·y al·dos·ter·on·ism

an adrenocortical disorder caused by excessive secretion of aldosterone and characterized by headaches, nocturia, polyuria, fatigue, hypertension, potassium depletion, hypokalemic alkalosis, hypervolemia, and decreased plasma renin activity; may be associated with small benign adrenocortical adenomas.

pri·mar·y al·dos·te·ron·ism

(prī'mar-ē al-dos'tĕr-ōn-izm)
An adrenocortical disorder caused by excessive secretion of aldosterone and characterized by headaches, nocturia, polyuria, fatigue, hypertension, potassium depletion, hypokalemic alkalosis, hypervolemia, and decreased plasma renin activity; may be associated with small, benign adrenocortical adenomas.
Synonym(s): Conn syndrome, idiopathic aldosteronism.

Conn,

Jerome, U.S. physician, 1907-1981.
Conn syndrome - an adrenocortical disorder caused by excessive secretion of aldosterone. Synonym(s): primary aldosteronism

pri·mar·y al·dos·te·ron·ism

(prī'mar-ē al-dos'tĕr-ōn-izm)
An adrenocortical disorder caused by excessive secretion of aldosterone.
Synonym(s): Conn syndrome, idiopathic aldosteronism.

aldosteronism

an abnormality of electrolyte balance caused by excessive secretion of aldosterone; hyperaldosteronism.

primary aldosteronism
that arising from oversecretion of aldosterone by an adrenal adenoma, characterized typically by hypokalemia, alkalosis, muscular weakness, polyuria, polydipsia and hypertension. Called also Conn's syndrome.
pseudoprimary aldosteronism
that caused by bilateral adrenal hyperplasia and having the same signs and symptoms as primary aldosteronism.
secondary aldosteronism
that due to extra-adrenal stimulation of aldosterone secretion; it is associated with edematous states, as in nephrotic syndrome, hepatic cirrhosis and heart failure.
References in periodicals archive ?
For cats with unilateral primary aldosteronism with no evidence of metastasis, adrenalectomy is the therapy of choice and is curative for both adenoma and adenocarcinoma with signs of hypokalemia or hypertension, with resolution of the clinical manifestations eliminating additional postoperative therapy (ASH et al.
Aldosterone producing adenoma and other surgically correctable forms of primary aldosteronism.
Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents.
In clinical practice, primary aldosteronism is equally reported in both sexes, with a peak incidence between ages 30 and 60 years; it is rarely seen in children.
Identification of the etiology of primary aldosteronism with adrenal vein sampling in patients with equivocal computed tomography and magnetic resonance findings: results in 104 consecutive cases.
Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.
Role of radiology in the management of primary aldosteronism.
Primary aldosteronism is the most frequent cause of secondary hypertension and is responsible for 5%-15% of cases of increased blood pressure among hypertensive populations (1).
Primary aldosteronism, traditionally seen as a rare, stump-the-experts-type disorder, is now accepted as the cause of 5%-10% of all cases of what has been considered essential hypertension.
Primary aldosteronism is a readily treatable disorder, either surgically or medically, depending upon the subtype.
Objective: PANOSTICS comprises the validation and clinical implementation of a versatile and cost effective diagnostic blood test for the detection of primary aldosteronism (PA) among hypertensive patients.

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