primary acquired melanosis

primary acquired melanosis

A condition of older adults, which is a unilateral, diffuse brown pigmentation of the conjunctiva; it may
1. Remain stationary or regress.
2. Slowly enlarge, but remain benign or.
3. Undergo malignant degeneration–17%–melanocytic atypia is a major predictor
of malignancy.
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References in periodicals archive ?
Primary acquired melanosis of the conjunctiva: Risks for progression to melanoma in 311 eyes.
The patient was subsequently referred to our center for evaluation and management of suspected primary acquired melanosis (PAM).
Differential diagnosis includes other conjunctival melanocytic lesions such as primary acquired melanosis (PAM), conjunctival melanoma or secondary pigmentation in conjunctival intraepithelial neoplasia (CIN III), and squamous cell carcinoma.
It is further subdivided into primary acquired melanosis (PAM) without atypia and PAM with atypia.
Another ocular lesion, primary acquired melanosis, can have anything from what looks like melanoma in situ to something as innocuous as hyperpigmentation.
About 75% will arise from cases of primary acquired melanosis with atypia.
The differential diagnosis of pigmented areas on the conjunctiva includes nevus, racial melanosis, primary acquired melanosis, secondary pigmentary deposition, and ocular melanoma.
3) Melanocytic lesions include naevus, melanoma racial melanosis, primary acquired melanosis and other ocular surface conditions like ocular melanocytosis and secondary pigmentary deposition.
Importantly, the authors discuss unique terminology of conjunctival melanocytic proliferations used by ophthalmic oncologists and provide a detailed update on the clinical and pathologic features of conjunctival nevi, primary acquired melanosis, and melanoma.
Another ocular lesion, primary acquired melanosis, can encompass several different histologic patterns, both benign and malignant.
Approximately 75% will arise from primary acquired melanosis with atypia.