primaquine


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primaquine

 [pri´mah-kwin]
an antimalarial agent effective against the extraerythrocytic forms of Plasmodium vivax and P. ovale and the gametocytes of P. falciparum, used especially in the treatment of relapsing vivax malaria; used orally as the phosphate salt.

primaquine

(prē′mə-kwēn′, -kwĭn, prī′-)
n.
A drug, C15H21N3O, used in its phosphate form as an antimalarial, especially to prevent relapses.

primaquine

A drug used in the treatment of Plasmodium vivax and Plasmodium ovale MALARIA. The drug is on the WHO official list.
References in periodicals archive ?
The patient recovered after outpatient treatment with mefloquine and primaquine.
The other major step by the panel was to add primaquine as a sixth option for primary prophylaxis, although it is a second-line drug because of its potentially serious adverse effects.
Classically, after ingestion of certain agents like sulfamides, antipyretics, nitrofurans and antimalarial medicines, like the primaquine and chloroquine, the patient develops fever, black color urine, ictericia and anemia.
The original recommendation (2) remains unchanged: all refugees of Congolese origin with splenomegaly should receive presumptive treatment with primaquine after arrival in the United States.
Clindamycin and primaquine therapy for mild-to-moderate episodes of Pneumocystis carinii pneumonia in patients with AIDS: AIDS Clinical Trials Group 044.
Moll intensified control measures in the Bavaro Zone, which include 1) presumptive treatment of all construction and hotel workers by using directly observed therapy with chloroquine and primaquine, and 2) mosquito control through residual and spatial insecticide spraying and application of larvicide to suspected breeding sites.
In industrialized countries, improved clinical and microbiological control after treatment and radical cure with primaquine can be achieved for malaria.
Treatment of chloroquine-resistant Plasmodium vivax with chloroquine and primaquine or halofantrine.
ovale were radically cured with chloroquine combined with primaquine; and persons who had P.
He was advised to take primaquine (15 mg/day for 2 wk), after confirming normal blood level of glucose-6 phosphate dehydogenase and discharged on Day 6.
She was prescribed chloroquine and primaquine. One month later, the mother was interviewed in Spanish, her native language; she stated that she had malaria diagnosed 2 years earlier in Guatemala and was treated with an unknown therapy.