Presbyacusis is highly similar to noise-induced deafness in clinical pathology.
Thus, the Myo3a mutant mouse model that we constructed was not only a good model for presbyacusis but also a satisfactory human disease model.
Ototoxicity, chronic suppurative Otitis media (CSOM), presbyacusis, impacted ear wax, rhinosinusitis, febrile illness and ear trauma were the common causes of hearing loss in Benin City in decreasing order of frequency.
22 aetiological factors were implicated for hearing loss, but ototoxicity, CSOM and presbyacusis were the commonest.
values in relation to noise-induced hearing loss.
Degenerative changes have been described in the maculae,15 the cristae ampullaris16 and in the vestibular nerve17 .All these will account for vertigo in presbyacusis
and some other conditions, which is a major risk factor predisposing to falls among the elderly,18 the significance of which lies in the high morbidity and indeed mortality, associated with falls occurring in this age group.
Effects of dietary restriction and antioxidants on presbyacusis
. Laryngoscope 2000;110(5 Pt 1):727-38.
Mitochondrial DNA deletions associated with aging and presbyacusis
. Arch Otolaryngol Head Neck Surg.
The type of hearing impairment noted, is similar to that of presbyacusis
, but those affected show a greater decrease in hearing than one would except at that age.
noise induced hearing loss is the second most common cause of sensory neural hearing loss.
There was no incidence of significant asymmetrical hearing loss in either the EH or MAV group; all audiograms revealed either normal sensitivity or bilateral sensorineural hearing loss consistent with presbyacusis
Audiometric alterations (presbyacusis
) are not linked to phenytoin toxicity, and hearing does not appear to be affected by toxic phenytoin levels.