For let-7a, a trend toward increased expression in the hypothalamus and pituitary was observed from prepuberty
to postpuberty but did not reach a significant level (p>0.05).
Thus, the aim of this study was to evaluate the effects on reproductive endpoints of the 3-MCPD-exposure from the prepuberty
. For this, testicular and epididymal histology and sperm parameters were analyzed, using the reproductive tract of Wistar rats as the experimental model.
Accordingly, the aim of the present 3-year longitudinal investigation was to study the increases in BMD values during pubertal maturation in rhythmic gymnasts and their age- and height-matched untrained control girls, and to evaluate the relationships between body composition and jumping performance parameters with increases in BMD values when entering from prepuberty
The prepubertal testis has classically been defined as a quiescent organ, but recent findings revealed that prepuberty
is a critical window for male reproductive system development; during this stage the process of testicular spermatogenesis and steroidogenesis is highly responsive to EDCs , finally resulting in disturbed spermatogenesis and higher incidence of testicular germ cell cancer .
A4 concentration changes significantly throughout prepuberty
, obtaining the greatest increase at late infancy for both sexes and the highest concentrations in children within peripubertal ages, where a sexual dimorphism with higher A4 concentration in girls were observed.
Carskadon has demonstrated that, while the adolescent brain is more capable at staying awake later in the day, it still requires the same amount of sleep as it did during prepuberty
. In other words, if we allow teenagers to push back their bedtimes by 2 hours but continue to demand that they be in school at 7:30 in the morning, we will continue to see the behavioral and physiologic damage related to sleep deprivation.
Both female and male children experienced a rapid improvement in the prepuberty
Hypothalamic samples from the four groups were obtained on the day of prepuberty
(postnatal 21 days, n = 5 per group), onset-puberty (the day of vaginal opening, about postnatal 24 days, n = 5 per group), and postpuberty period (establishment of two regular estrous cycles, about postnatal 34 days, n = 5 per group).
 Rapid rise in the number of patients presenting with cervical/vaginal discharge especially VVC is due to following reasons: (1) Inadvertent use of antibiotics; (2) Increased referral of pregnant women from gynaecology department under the Prevention of Parent to Child Transmission of HIV/AIDS programme (PPTCT); (3) Increased use of contraceptives; (4) Change of certain behaviours like use of tampons, douches, deodorants, local antiseptics, tight fitting underclothing etc.; (5) Miscellaneous causes like increase in prevalence of diabetes mellitus, younger age of sexual contact, prepuberty
Transfer from prepuberty
to puberty: effects of three years of training.
Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization- induced stress from prepuberty
. Braz J Med Biol Res 1998; 31: 1443-8.
(1) About 15% of the general population can affect migraine with a male: female ratio of about 1:1 in prepuberty
and 1:3 in post pubertal age.