preproprotein

preproprotein

 [pre″-pro-pro´tēn]
any precursor of a proprotein.

pre·pro·pro·tein

(prē'prō-prō'tēn),
A precursor to an inactive secretory proprotein.

preproprotein

/pre·pro·pro·tein/ (-pro-pro´tēn) any precursor of a proprotein.

preproprotein

any precursor of a proprotein.
References in periodicals archive ?
Largely produced in the liver and the intestine (6), PCSK9 is synthesized in the endoplasmic reticulum (ER) as a preproprotein of692 amino acid residues (6).
BACE-1 is synthesized as a 501-amino acid-long preproprotein [relative molecular mass ([M.
bp Homo sapiens kallikrein KLK1-IRIII AY429508 992 1 isoform 3 preproprotein (KLK1) mRNA, complete cds, alternatively spliced Homo sapiens kallikrein 2 KLK2-IRIII AY429509 1458 isoform 5 preproprotein (KLK2) mRNA, complete cds, alternatively spliced Homo sapiens mRNA for KLK3-IRIII AJ310938 1603 putative preproPSA-RP2 (KLK3) gene, transcript 2 Homo sapiens kallikrein 4 KLK4-IRIII AF148532 859 splice variant (KLK4) gene, complete cds, alternatively spliced Homo sapiens kallikrein 15 KLK5-IRIII AY461805 1301 isoform 3 preproprotein (KLK5) mRNA, complete cds; alternatively spliced Homo sapiens kallikrein 15 KLK15-IRIII AY373373 1398 isoform 5 preproprotein (KLK15) mRNA, complete cds; alternatively spliced Predicted Protein protein accession length, GenBank submission name no.
The nucleotide sequence of the five coding exons of hKLK2 predicts the production of a 261-amino acid preproprotein that includes a signal peptide of 17 amino acids and an activation peptide of 7 amino acids, similar to the structure of hPSA [22].