anticipation

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an·tic·i·pa·tion

(an-tis'i-pā'shŭn),
1. Appearance before the appointed time of a periodic symptom or sign.
2. Progressively earlier age of manifestation of a hereditary disease in successive generations; may be factitious (because of heightened awareness of early signs of the disease or because these signs are more conspicuous in the young) or authentic (because of progressive loss of epistatic and modifier genes by recombination and segregation, or because of expansion of unstable alleles in successive generations).
3. An increase in the severity of a phenotype in successive generations of a family, often associated with an increase in the number of trinucleotide repeats in a causative gene (e.g., fragile X syndrome, myotonic dystrophy, Huntington disease).

anticipation

An anomalous pattern of inheritance, first identified by researcher Stephanie Sherman, in which the manifestations of a particular inherited disorder (Sherman studied Fragile X syndrome) are more marked with each passing generation of patients who are at risk of a certain mutation. Anticipation results from two genetic events; a premutation (e.g., insertion of increasing number of the trinucleotide repeat CGG), which eventually passes a threshold and becomes an active mutation in the progeny.

an·tic·i·pa·tion

(ăn-tis'i-pā'shŭn)
Foreknowledge or expectation.
[L. anticipatio, fr. anticipo, to take before]

anticipation

The occurrence of a hereditary disease at progressively earlier ages, and in progressively more severe form, in successive generations. This is a feature of a range of conditions that includes myotonic dystrophy, the fragile X syndrome and Huntington's disease.

Patient discussion about anticipation

Q. Can anyone help us by giving some dietary information to reduce on her stress? Thank you in anticipation. My aunt is suffering from breast cancer for the past 3 years. She lives in a village. She feels good after the treatment. She is having poor immunity due to which she gets cold easily. She often gets sick. This has to a great extent affected her sleep pattern also. Doctor has advised her to control the stress and also to reduce on barbeques, as she takes them a lot. We are helping her to find different ways to reduce the stress. Can anyone help us by giving some dietary information to reduce on her stress? Thank you in anticipation.

A. what we eat has an immense effect on our mood, and the other way around...
eating chocolate raises the amount of serotonin in our brain, carbohydrates also cause hormones in our body to change and calm us down. but i think the best nutritional value comes from Omega-3 fatty acids. the brain cells are built from them and they helps membrane to gain stability.

More discussions about anticipation
References in periodicals archive ?
In 2006, five residents in Phiri township (a part of Soweto) filed suit against the city of Johannesburg and the Johannesburg water utility, alleging prepayment meters are unconstitutional.
While losing the ability to tweak cash flows to one's particular needs may inconvenience many borrowers and push some borrowers at the margin out of the market, economic theory suggests that prepayment penalties may be playing a more fundamental role in the functioning of subprime mortgage markets.
Mortgage rates are affected by not only the real estate market risk factor, but also by the term, default, and prepayment risk factors.
Director Wendy Davies said: "Many prepayment customers are unaware they can change to a different payment, or even a different supplier, without incurring any charges."
Finally, the prepayments did not afford the respective grandchildren any additional rights or privileges, and did not guarantee the child's acceptance and enrollment at the school.
The Quoted Yield and the Assumed Prepayment Rate on the Underlying Mortgages--The return actually realized by an investor may differ substantially from the quoted yield if actual prepayments on the underlying mortgages differ substantially from the assumptions used to compute the quoted yield.
For example, when interest rates rise, prepayment speeds will slow and the value of an IO will increase.
Second, the taxpayer's prepayment is itself a noisy signal of the information that was available to the taxpayer as of the time of the prepayment, which in turn affects the reporting strategies of high-income taxpayers.
"If someone has good credit, [they] may be offered a much lower interest rate in exchange for the prepayment penalty.
Finally, to address concerns about monitoring and valuing the effects of adverse prepayment selection in the TBA market, Bear Stearns will provide two new tools to its MBS customers:
This model incorporates prepayment uncertainty by computing the value of the promised mortgage payments separately from the value of the prepayment rights.