Indeed, increased 5-HT concentration in the preoptic
area, a brain area that controls the autonomic thermoeffectors (31), induces higher heat storage rate and reduces performance following icv injection of TRP (Figure 2) (29).
In a paper appearing online Thursday in the journal Science, researchers from Stanford University looked at the median preoptic
nucleus - a region of the brain that previous research had suggested was linked to the sensation of thirst.
The medial preoptic
nucleus (MPN), a key region underlying the motivation to vocalize and mate (Alward et al.
Leptin-dependent neuronal NO signaling in the preoptic
hypothalamus facilitates reproduction.
24] The preoptic
area/anterior hypothalamus (PO/AH) is a responsive structure to [PGE.
The majority of LHRH-synthesizing neurons are localized within the brain preoptic
area and the region just posterior to it referred to as the anterior hypothalamic area.
This GABA influx inhibits inhibitory neurons in the preoptic
area in the hypothalamus, which is the area in charge of temperature control, among other functions.
increases the cFos expression in GABAergic neurons of the ventrolateral preoptic
area of Sprague-Dawley rats, which suggests that NHBA activates the sleep centre in the anterior hypothalamus, producing significant sedative and hypnotic effects (Zhang et al.
Oxytocin in the medial preoptic
area facilitates male sexual behavior in the rat.
Experiments on these questions dating back 80 years, using rats and mice, have repeatedly pointed to a tiny brain region known as the preoptic
hypothalamus (POA) as the site that detects the bodys warmth.
Androgens stimulate preoptic
area Na+, K+, -ATPase activity in male rats.
It has been previously shown that GnRH-immunoreactive fibers are present in regions of the brain known to regulate sexual behavior including the bed nucleus of the stria terminalis (BnST), the medial amygdala (mAg) and most notably, the medial preoptic
area (mPOA) (18).