A study in Lahore concluded that 76.5% of the parents have knowledge about
prenatal screening but only 33% of the parents knew that thalassemia trait can be detected before marriage.
The findings add new perspectives regarding how sonographers manage their daily work and regarding the significance of sonographers' communication within
prenatal screening.
Further exploring strategies that improve
prenatal screening practices in the health care system (e.g., provider education, standing orders, and opt-out testing) is essential for addressing challenges with screening adherence, even in areas with mandated screening laws.
It is possible to include a fifth fluorophore and further lengthen the 3' primer to exponentially improve the throughput, allowing the interrogation of more than 4 chromosomes/regions in a single reaction, which would make NiPS an ideal alternative to MPS-based techniques in
prenatal screening of common aneuploidies.
Prenatal Screening for Genetic Diseases: An Overview
The Canadian Guidelines on Sexually Transmitted Infections recommend that
prenatal screening be performed in the first trimester, at mid-gestation (i.e., 28-32 weeks) and again at delivery among pregnant women who are at high risk of acquisition of syphilis, or in areas that are experiencing heterosexual syphilis outbreaks.
Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in
prenatal screening [published online ahead of print March 18,2015].
It is worth noting that there is a non-invasive
prenatal screening test (the Harmony test) that analyses cell-free DNA in the maternal blood and will identify 99% of fetuses with trisomy 21, 97% of fetuses with trisomy 18, and 92% of fetuses with trisomy 13.
The high correlation coefficients for both markers indicate that DBS from finger prick can be used reliably in a
prenatal screening setting, as a less costly and minimally invasive alternative for venipuncture serum, with great logistical advantages.
Government should work to promote
prenatal screening. Centers should be created for diagnosing these disorders during pregnancy, thereby limiting the number of affected infants being born with a rare disease.
Lexington, KY, April 12, 2013 --(PR.com)-- On Thursday, April 4, 2013, the American College of Medical Genetics and Genomics (ACMG) released their policy statement on non-invasive
prenatal screening (NIPS) (http://www.acmg.net/docs/nips-GiM_galley_text_130301.pdf).
Non-invasive
prenatal screening during pregnancies is available for parents and it is strongly recommended by experts.
