In human premixed insulins, 2/3rd dose is prescribed before breakfast, and 1/3rd before dinner.
Why is premixed insulin the preferred insulin Novel answers to a decade- old question.
A randomized controlled trial conducted in 15 countries found that once daily premixed aspart insulin was clinically equivalent to insulin glargine in reducing HbA1c.
In the 1-2-3 study, 41% of all subjects were able to achieve target HbA1c with once daily premixed aspart.10 Similar results are noted in studies carried out in primary care settings which have demonstrated that patients are able to safely self-titrate their dose requirements of premixed insulin.11
Premixed insulin has traditionally been perceived as twice-daily insulin, and can be initiated as such.
Premixed insulin can be used for intensification of therapy as well, if the initiation regime of once or twice daily injections is unable to achieve target.
Premixed insulin, if prescribed once daily, should be offered with the main meal of the day.
If taken twice daily, premixed insulin is usually prescribed with breakfast and with dinner.
Persons who consume a heavy breakfast (parathas, for example), may benefit from a dual premixed regime.
Despite unsatisfactory shipments of cement over the past three years, Taiwan Cement has seen the proportion of premixed concrete to overall sales increase to over 40% in 2010 from less than 40% three years ago.
Yadong Premixed Concrete Co., which Asia Cement has over 90% stake, currently has 22 premixed-concrete plants around the island.
Goldsun said it would invest over NT$300 million to set up two or three new plants of premixed concrete in central Taiwan this year.