In this paper, we carry out a systematic review and meta-analysis of published randomised controlled trials (RCTs) to review the effectiveness of current chemopreventive agents in treatment of oral premalignant
lesions and prevention of their progression to oral cancer.
8% of different oral lesions, premalignant
and benign lesions, and 6.
field often requires a much longer period of approximately 67-96 months to progress into an invasive carcinoma.
Among the Asian patients, one-third presented with malignant or premalignant
, one-third presented with infectious, and one-third presented with inflammatory conditions.
Correlation of pap smear and colposcopy in relation to histopathological findings in detection of premalignant
lesions of cervix in a tertiary care centre.
Amongst the 64 premalignant
oral lesions studied, leukoplakia comprised of 14 cases (21.
While most cases of HPV infection spontaneously regress within one to two years, in some cases, a transforming event occurs, frequently as a result of integration of the high risk HPV viral genome into the genome of cervical basal epithelial cells, leading to the loss of normal cell cycle regulatory mechanisms and the development of premalignant
lesions of the squamous and/or glandular mucosa.
The test is used to evaluate common white and red lesions to detect the presence of premalignant
and early stage oral cancers.
lesion is a morphologically changed tissue which has greater risk of malignant transformation in comparison with normal tissue.
Various genetic and molecular alterations are observed in oral premalignant
and malignant lesions due to consumption of tobacco.
lesions and oral squamous cell carcinoma are significant health problems influenced by different predisposing factors and genetic alterations .
Pathologists and imaging specialists from the US focus on malignant tumors and also cover inflammatory disorders, benign lesions, hyperplasias, and premalignant
conditions, as well as the imager's perspective, the advantages and disadvantages of aspiration and core needle biopsy, and ancillary testing like hormonal and molecular markers.