Therefore, the aim of this study is the assessment of the current knowledge, attitudes and performance of dentists about premalignant
Oral squamous cell carcinoma is a life threatening health problem in all over the world especially in de- veloping countries.9 OSCC is the sixth most common cancer in the world10 but it is the second most common cancer in Pakistan.11 Oral cancer is usually diagnosed in the old age especially after 60 years but now there is an alarming increase in the incidence of oral cancer at earlier age.12 OSCC is staged on the basis of clinical appearance and graded on the basis of histopathological features.13 Various genes and proteins are involved in the pathogenesis of oral premalignant
and OSCC which affects the proliferative and apoptotic pathways.
We also determined the sensitivity and specificity of acetowhitening in distinguishing premalignant
and malignant lesions of the cervix.
Hence, Ki-67 can be employed to measure the growth fraction of normal tissues, as well as premalignant
and malignant lesions.
Groups II, III: 20 patients were chosen to have potentially premalignant
lesions; according to previous literature [19,28].
Toluidine blue is an effective adjunctive screening tool for identifying premalignant
lesions or oral cancer recurrences in those who have already been diagnosed with oral dysplasia or oral cancer.
-- Because actinic keratoses are the most common lesions with premalignant
potential in the skin, knowing how to predict their malignancy can be lifesaving, according to Dr.
These researchers ("Detection of human papillomavirus DNA in feline premalignant
and invasive squamous cell carcinoma, Veterinary Dermatology, 2011) determined the prevalence of papillomavirus in cutaneous and non-cutaneous precancerous or cancerous lesions (SCCs) in 84 cats using virus genetic detection (PCR).
It predominantly occurs in adults older than 40 years, although younger adults and children can be affected.1-3 Although several cases of malignant transformation of OLP have been reported in the literature, controversy still exists about considering OLP as a premalignant
AK is a premalignant
condition of thick, scaly or crusty patches of skin.
It can be concluded that the study proved the presence of Tregs in cervical lesions and their possible role in the progression of premalignant
lesions to malignant lesions.
This lesion may be associated with a benign, premalignant
,or malignant lesion at its base.