In all mammals, the type B/B1 spermatogonia undergo mitosis to give rise to the cells that represent the beginning of meiosis, the preleptotene
46) FSH is responsible for the development and differentiation of spermatogonia through different stages namely spermatogonia, preleptotene
, leptotene, early pachytene, late pachytene, and secondary spermatocytes after the attainment of puberty.
In meiosis the process is divided into six stages: preleptotene
, leptotene, zygotene, pachytene, diplotene, and diakinesis.
Population of preleptotene
, pachytene, secondary spermatocytes and step-19 spermatid were declined by 60.
84%) deviation) (c) Testicular cell counts (number/10 cross section) Primary spermatocytes Preleptotene
Pachytene Group-I 19.
The results showed decreased germ cell number followed by compensatory spermatogonial proliferation by 16 days (as shown by thymidine-H3 testicular uptake), increased apoptotic rate, mainly of spermatogonia, and preleptotene spermatocytes.
Apoptosis of preleptotene spermatocytes (arrows) and step (9) spermatids in stage IX are seen in Fig.
These results ate in keeping with the observation that the majority of apoptotic cells revealed by the TUNEL technique corresponds to spermatogonia (and also preleptotene spermatocytes).
The most susceptible cells were actively dividing spermatogonium and spermatocytes up to preleptotene
The population of preleptotene and pachytene spermatocytes were decreased by 64.
26%; spermatogonia and preleptotene spermatocytes were decreased by 59.