preimplantation genetic diagnosis


Also found in: Dictionary, Thesaurus, Legal, Acronyms, Encyclopedia, Wikipedia.
Related to preimplantation genetic diagnosis: Designer babies

preimplantation genetic diagnosis (PGD)

in assisted reproductive technology, the determination of chromosomal abnormalities in the embryo before it is transferred to the uterus.

preimplantation genetic diagnosis

In assisted reproduction, the testing of a fertilized egg for heritable illnesses before the ovum is inserted into the female.
See also: diagnosis

preimplantation genetic diagnosis

The use of genetic analysis in the course of vitro fertilization to ensure that a baby does not possess a known genetic defect of either parent. After analysis of the embryos formed, only those free of defect are implanted in the mother's womb. A new method, developed in 2006, involves taking a single cell from the IVF embryo, amplifying the entire genome to provide many copies, and then comparing the chromosome containing the known family mutation with those of other family members by standard DNA fingerprinting techniques.
References in periodicals archive ?
Scoring criteria for preimplantation genetic diagnosis of numerical abnormalities for chromosome X, Y, 13, 16, 18 and 21.
Preimplantation Genetic Diagnosis Testing Market - Global Diagnostic Applications and End Users Analysis and Forecast 2013-2020, the global Preimplantation genetic diagnosis testing market was valued at USD 78 Million in 2015 and is estimated to reach USD 116 Million by 2020, at a CAGR of 8.
This evaluation aids in the development of a care plan and is also an opportunity to discuss risks to the mother and the neonate, partner carrier screening, and options for prenatal or preimplantation genetic diagnosis.
Headquartered in Livingston, New Jersey, Reprogenetics is a genetics laboratory specialising in preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD).
Increased efficiency of preimplantation genetic diagnosis for aneuploidy by testing 12 chromosomes.
Using a reorganized structure, this edition has been updated to include the latest information on the Human Genome Project, identification of new classes of RNA molecules, new molecular genetic and chromosome analysis techniques, further development of preimplantation genetic diagnosis, improved methods for antenatal and neonatal screening, self-assessment questions, and case study scenarios.
We used pluripotent stem cell lines derived from human embryos characterized during preimplantation genetic diagnosis as carrying the gene for DM1," Martinat said.
The single-blastomere technology uses a one-cell biopsy approach similar to preimplantation genetic diagnosis (PGD), which is widely used in the in vitro fertilization (IVF) process and does not interfere with the embryo's developmental potential.
The technique - known as preimplantation genetic diagnosis - has already been used in the UK to choose babies free of inherited disorders such as cystic fibrosis.
Comparison of blastocyst transfer with and without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial.