pregnane


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pregnane

 [preg´nān]
a crystalline saturated steroid hydrocarbon; β-pregnane is the form from which several hormones, including progesterone, are derived; α-pregnane is the form excreted in the urine.

preg·nane

(preg'nān),
Parent hydrocarbon of two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β-ethyletiocholane). 5β-Pregnane is the parent of the progesterones, pregnane alcohols, ketones, and several adrenocortical hormones and is found largely in urine as a metabolic product of 5β-pregnane compounds.

pregnane

/preg·nane/ (preg´nān) a crystalline saturated steroid hydrocarbon, C21H36; β-pregnane is the form from which several hormones, including progesterone, are derived; α-pregnane is the form excreted in the urine.

preg·nane

(preg'nān)
Parent hydrocarbon of the progesterones, pregnane alcohols, ketones, and several adrenocortical hormones.
Compare: bioregulator

pregnane

one of the two major types of steroid hormone involved in female reproductive processes; includes progesterone.
References in periodicals archive ?
Several furostane and pregnane saponins have been isolated from the mesocarp of the fruit (Farid et al.
Animal data for the anticonvulsant perampanel (Fycompa) suggest risk, but the absence of human pregnane experience prevents a full assessment of the embryo-fetal risk.
The pregnane X receptor (PXR) plays an important role in regulation of the expression of proteins involved in bile acid homeostasis.
The latest research at Carolina State University, which reveals how pregnane glycosides (the actives in Caralluma) inhibit appetite, validates the clinical results and puts Caralluma at the head of the class of natural weight loss products.
Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta.
Cholesterol Detoxification by the Nuclear Pregnane X Receptor.
For example, the DHS asks women, for each of their births in the last five years, "Just before you became pregnane with, did you want to have more children then, did you want to wait longer or did you want no more children?
The role of pregnane neurosteroids in ethanol withdrawal: Behavioral genetic approaches.
Through activation of the pregnane X receptor, which results in increased expression of multiple drug metabolising enzymes and transporters, rifampicin increases the oral clearance of many medications.
A cardenoide tetraglycoside, oxyline isolated from roots [4] and polyhydroxy pregnane glycosides, alpinoside A, B and C from aerial parts of the plant [5] were reported.
The presence of both gammacerane and pregnane shows that all the oil shales have been deposited in a saline environment.
119) The court further stated that the utility of the claimed compounds, which were described in specification as being of the "androstane and pregnane series," need not be "conclusively predicted.

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