Background: Pregnancy luteoma is a rare non neoplastic condition of the ovary.
Histopathological examination revealed solid aggregates of large cells with abundant eosinophilic cytoplasm; diagnosis of pregnancy luteoma was given.
Keywords: Ectopic pregnancy, Ovarian masses, Pregnancy luteoma.
Pregnancy Luteoma in Ectopic Pregnancy: A Case Report.
The etiology is unclear and it has been postulated that the pregnancy luteoma arises from pre-existing luteinised stromal cells, which respond in an exaggerated manner to the elevated levels of gonadotropin during pregnancy.
Based on the clinical and histopathological findings a diagnosis of bilateral pregnancy luteoma was rendered.
Pregnancy luteoma is a non-neoplastic lesion of the ovary occurring during pregnancy and is known to spontaneously regress, which begins within days after the delivery.
Pregnancy luteoma represents a physiologic response during pregnancy and often regresses spontaneously in postpartum period.
Several such entities are discussed in this review, including microglandular hyperplasia of the cervix mimicking well-differentiated endometrial and endocervical adenocarcinoma, reactive epithelial changes in the fallopian tubes mimicking adenocarcinoma or carcinoma in situ, atypical and hyperplastic changes in endometriosis, and pregnancy changes in the ovary including pregnancy luteoma and large solitary luteinized follicular cyst of pregnancy and puerperium.
Two such entities that may be mistaken clinically and pathologically for neoplasms are pregnancy luteoma and solitary luteinized follicle cyst of pregnancy and the puerperium.
Pregnancy luteoma is a benign, hyperplastic lesion that may be mistaken for a neoplasm, thus leading to unnecessary oophorectomy.
They differ from pregnancy luteoma in that they are usually unilateral and solitary, as opposed to the multinodular and bilateral lesions seen in pregnancy luteoma.