Many drugs can provide preemptive analgesia
, including opioids, (2-5) but there is a concern that the incidence of side effects associated with opioids will increase, because of the synergistic effect of preemptive opioid with intraoperative and postoperative opioids.
Ko-Iam, "Effects of preemptive analgesia
in laparoscopic cholecystectomy: a double-blind randomized controlled trial," Surgical Endoscopy, vol.
Concept of preemptive analgesia
is not new in dentistry, various drugs like analgesics, steroids and antianxiety drugs have been under clinical trial.12
. Only 32 cases had preemptive analgesia
in this study; it was found that preemptive analgesia
did decrease incidence of chronic pain but due to limited number of cases it is difficult to recommend the same.
New concepts in acute pain therapy: Preemptive analgesia
. Am Fam Physician.
The study of preemptive analgesia
over the past 20 or more years has focused almost exclusively on one goal: reducing immediate postoperative pain, usually with narcotic consumption as the primary outcome measure.
The goal of PNB is preemptive analgesia
(minimizing the pain before it is perceived).
Advantages of providing preemptive analgesia
include a balanced anesthetic regimen and pain relief during relatively smoother recoveries from painful procedures.
After preemptive analgesia
, an abdominal midline surgical incision was made under anesthesia with 2% isoflurane delivered by an anesthesia apparatus.
The idea behind preemptive analgesia
is to head off pain by blocking the central nervous system's response before the surgery occurs.
Reda, "Comparison of the preemptive analgesia
of low dose ketamine versus magnesium sulfate on parturient undergoing cesarean section under general anesthesia," Egyptian Journal of Anaesthesia, vol.