preclinical studies

preclinical studies, a term used to describe research done before a clinical study. May be laboratory or epidemiologic research.
References in periodicals archive ?
In preclinical studies, Biolex has shown that BLX-883 is comparable to commercially available alfa interferon and that it can be produced cost-effectively using Biolex' proprietary LEX System in the company's cGMP manufacturing facilities.
Cortex has targeted a lead AMPAKINE(TM) compound for development, and preclinical studies at five additional research centers in the United States have confirmed earlier findings of enhanced short- and long-term memory.
VistaGen recently announced positive results from preclinical studies of AV-101, its lead drug candidate, in animal models of neuropathic pain, as well as studies relevant to Parkinson's disease.
Preclinical studies have shown that using PG490-88Na can significantly inhibit growth of a broad range of human tumor cells.
Preclinical studies for pre- and post- exposure prophylaxis of HIV infection are continuing on MEDI-488, the company's broadly-reactive HIV human monoclonal antibody, with the first chimpanzee studies expected to begin later this month.
Preclinical studies of DDP733 established the compound's prokinetic properties (the ability to promote the motility of the GI tract).
Vibriolysin Topical has displayed promising efficacy in numerous preclinical studies related to the debridement (cleaning) of dead tissue resulting from serious burns.
CT-322 is a proprietary Adnectin(TM) protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis pathway.
is conducting preclinical studies, and lead compounds for sleep disorders and/or attention deficit/hyperactivity disorder, which were derived from the collaboration and for which the Company is conducting preclinical studies.
an emerging biopharmaceutical company, focused on stem cell technologies, to discover, develop and commercialize novel small molecule drugs and protein therapeutics for neurological disorders and diabetes, announced positive results from preclinical studies of AV-101, its lead drug candidate, in acute and chronic neuropathic pain animal models.
In contrast, preclinical studies with HE3286 indicate that it does not act on the PPARgamma receptor and does not have the undesirable effect of weight gain seen with the glitazone class.
MCT-465 in preclinical studies successfully reduced pulmonary influenza virus levels 1,000-fold in animal models, and has demonstrated effectiveness in reducing virus levels of HIV and HCV in animal models.