precancer


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Related to precancer: precancerous, precancerous lesion

precancer

 [pre´kan-ser]
a condition that tends to become malignant (see cancer). adj., adj precan´cerous.

pre·can·cer

(prē-kan'sĕr),
A lesion from which a malignant neoplasm is believed to develop in a significant number of instances, and that may or may not be recognizable clinically or by microscopic changes in the affected tissue.

precancer

(prē′kăn′sər)
n.
A precancerous condition.

precancer

Premalignant, preneoplasia Any of a broad group of conditions with a malignant predisposition; epithelial precancers may be
1. Glandular–eg, adenomatous hyperplasia–endometrium and adenomatous polyps–colon, stomach, which evolve towards adenocarcinoma of their respective organs or.
2. Squamous–eg, dysplasia of the uterine cervix or other urogenital mucosae; premalignant lesions of mesenchymal origin include prelymphoma and 'presarcoma'–an ad hoc coinage, the latter of which may be due to predisposing factors–eg, osteosarcoma may arise in Paget's disease of bone, radiation, hereditary multiple exostoses, polyostotic fibrous dysplasia, enchondroma, Maffucci's enchondromatosis; osteosarcomas may be induced experimentally by various trauma–chemical–eg, turpentine, mechanical– eg, local pressure, indwelling foreign bodies, ischemia–eg, vessel clamping. Cf Preneoplastic state. See Fragile X syndrome, Hereditary neoplasms, Premalignancy.
Precancer
Chromosome breakage syndromes Bloom syndrome, Fanconi syndrome
Genodermatoses Albinism, dyskeratosis congenita,epidermodysplasia verruciformis, polydysplastic epidermolysis bullosa, Werner syndrome, xeroderma pigmentosa
Hamartomatous syndromes Multiple exostoses, neurofibromatosis, Peutz-Jegher syndrome, tuberous sclerosis, von Hippel-Lindau syndrome
Immunodeficiency syndromes Ataxia-telangiectasia, Wiskott-Aldrich syndrome, X-linked agammaglobulinemia 
.

pre·can·cer

(prē-kan'sĕr)
A lesion from which a malignant neoplasm is believed to develop in a significant number of instances, and which may or may not be recognizable clinically or by microscopic changes in the affected tissue.
References in periodicals archive ?
The primary aim was to assess the impact of HIV infection on HPV acquisition, persistence, and progression to precancer cervical changes and to cervical cancer.
Among women aged 15 to 26 years, vaccines reduced the risk of cervical precancer associated with HPV16/18 from 341 to 157 per 10,000.
Tsai noted that the CTC assay's sensitivity of nearly 77% for precancer compares favorably with that of a variety of other screening tests, such as the stool guaiac test for fecal occult blood (2%-10%), FIT alone (23.8%), and a stool DNA test combined with FIT (42%), and, in fact, falls within the range reported for colonoscopy (76%-94%).
Huang, "In vivo diagnosis of cervical precancer using Raman spectroscopy and genetic algorithm techniques," Analyst, vol.
Even today, one wonders about the availability of screening and treatment for cervical precancer for rural women who know about the service availability and somehow manage to surmount the many barriers to accessing services [11,12].
HPV testing led to a 15.8 percent overall increase in the detection of cervical precancers, and time to detection was much shorter (a median of 103 days versus 393 days).
Salivary lipid peroxidation product malondialdehyde in precancer and cancer.
DAPK promoter hypermethylation in tissues and body fluids of oral precancer patients.
The precancer risk of betel chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in Southern Taiwan.
They also recommend against screening after hysterectomy with removal of the cervix in women with no history of high-grade precancer or cervical cancer, and against screening with HPV testing in women younger than age 30, either alone or with cytology.
Recent studies at Thomas Jefferson University show that retinoic acid, a derivative of vitamin A, has been proven to turn precancer cells back to healthy breast cells.
Clinical features of oral submucous fibrosis; Common precancer in Sri Lanka caused by arecanut.