HIV pre-exposure prophylaxis
in men who have sex with men and transgender women: a secondary analysis of a phase 3 randomised controlled efficacy trial.
Changes in renal function associated with oral emtricitabine/tenofovir disoproxil fumarate use for HIV pre-exposure prophylaxis
for HIV: can it be implemented in the real world?
On demand antiretroviral pre-exposure prophylaxis
for HIV intection in men who have sex with men (IPERGAY).
The guidance is based on clinical trials indicating that HIV-negative people taking a daily dose of oral antiretroviral medication, known as pre-exposure prophylaxis
(PrEP), to reduce the risk of infection, is both safe for people to use and effective in preventing HIV.
The data supporting the approval of Truvada for HIV prevention in uninfected adults, a strategy called pre-exposure prophylaxis
(PrEP), comes primarily from two large placebo-controlled trials that showed taken once daily, the drug significantly reduced the risk of HIV infection in uninfected adults at high risk of acquiring the virus through sex.
The study had enrolled 5,029 sexually active, HIV-negative women to test the daily use of two different oral antiretrovirals as pre-exposure prophylaxis
(PREP): tenofovir and a combination tablet containing emtricitabine and tenofovir (known by the trademark Truvada), and a vaginal gel containing 1% tenofovir.
PrEP stands for pre-exposure prophylaxis
or prevention, one of several bio-medical prevention strategies being tested today.
BioThrax is the only FDA approved product for pre-exposure prophylaxis
of anthrax infection.
We call it pre-exposure prophylaxis
, we do not call it a vaccine, because medical care should still be sought if [a person is] bitten," she emphasized.
The study will evaluate injections of cabotegravir given every two months compared with daily oral pre-exposure prophylaxis
(PrEP) with emtricitabine/tenofovir disoproxil fumarate.
It comes after recent evidence suggested that the approach - known as pre-exposure prophylaxis
(PrEP) - can be a highly effective method in preventing the spread of the disease, should the drugs be taken regularly.