pre-eclampsia


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Related to pre-eclampsia: placenta previa, HELLP syndrome, Gestational diabetes, disseminated intravascular coagulation, IUGR

eclampsia/pre-eclampsia

(From Greek eklampsis, shining forth) Metabolic toxemia of pregnancy Obstetrics A condition which usually develops in late pregnancy or the immediate puerperium Clinical HTN, hemoconcentration, sodium retention with resultant edema Lab Albuminuria, proteinuria, hypoproteinemia, ↑ nitrogen/BUN; pre-eclampsia is most common in primigravidas, after the 24th gestational wk, but may occur as soon as trophoblastic tissue is present Treatment If mild, bed rest and sedation; if severe, antihypertensives–eg, vasodilators, α methyldopa; if convulsions, magnesium sulfate. See HELLP syndrome.

pre-eclampsia

A syndrome of high blood pressure (HYPERTENSION), fluid accumulation in the tissues (OEDEMA) and protein in the urine (albuminuria) that becomes apparent in the second half of pregnancy. Pre-eclampsia is primarily a placental disorder with damage to the inner lining (endothelium) of placental blood vessels. Oxygen FREE RADICALS cause endothelial cell damage, and may lead to reduced NITRIC OXIDE production, so that blood vessel widening (vasodilatation) is interfered with. Pre-eclampsia is a warning of the dangerous complication of ECLAMPSIA-a condition of seizures carrying a high maternal and fetal mortality. A major reason for antenatal care is to monitor for pre-eclampsia and to treat the condition, induce labour or perform a Caesarean section. It has been shown that abnormally high levels of circulating angiogenic factors such as vascular endothelial growth factor and soluble fms-like tyrosine kinase 1 predict the development of pre-eclampsia.
References in periodicals archive ?
She had no idea she had the most severe form of pre-eclampsia until a routine check-up at hospital revealed her life was at risk and Amy was too small to survive.
Back in September 2010, after a problem-free 36 weeks, my midwife discovered my blood pressure was too high and I had protein in my urine - classic signs of developing pre-eclampsia.
35) If a pregnant woman with pre-eclampsia develops seizures, then the disorder is classified as eclampsia.
Those most at risk are women under 18 or over 40, women who are obese, have had pre-eclampsia before or already suffer from high blood pressure, diabetes or certain other conditions.
6] Although there are limitations to 24-hour urine collections, the use of PCR for the diagnosis of pre-eclampsia has been controversial, with discordant conclusions compared with 24-hour urine collections.
However, in pre-eclampsia, this rise and fall is considerably lower throughout the pregnancy, and levels are strikingly lower when the condition presents clinically.
Pre-eclampsia is a serious condition where abnormally high blood pressure and related pathology develop during pregnancy.
The incidence of hypertension in the study was 19% and that of pre-eclampsia 5%.
I didn't have headaches although I was a bit swollen up, but I had too much protein in my urine and it was obvious to the doctors that I was suffering from pre-eclampsia.
Pre-eclampsia is characterised by high blood pressure and high levels of protein in the urine.
while up to five percent of first-time mothers will develop pre-eclampsia.
Indication: Pre-eclampsia (pregnancy induced hypertension)