prazosin


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Related to prazosin: Prazosin hydrochloride

prazosin

 [prah´zo-sin]
a postsynaptic alpha-adrenergic blocking agent that acts as a peripheral vasodilator; administered orally as the hydrochloride salt as an oral antihypertensive agent.

prazosin

(prā′zō-sĭn)
n.
A crystalline vasodilator, C19H21N5O4, used in the form of its hydrochloride to treat hypertension.

prazosin

Minipress® An alpha blocker used as an antihypertensive

prazosin

A drug that widens arteries (vasodilator) and is used in the treatment of high blood pressure (HYPERTENSION), HEART FAILURE and RAYNAUD'S PHENOMENON. The drug is on the WHO official list. A brand name is Hypovase.
References in periodicals archive ?
Low-dose prazosin in patients with muscle cramps during hemodialysis.
Rats were pretreated with WAY100635 (0.1 mg/kg, s.c., a selective 5-HT1A receptor antagonist), ketanserin (5 mg/kg, i.p., a preferential 5-HT2A receptors antagonist), prazosin (1 mg/kg, i.p., an [alpha]1-adrenoceptor antagonist), yohimbine (1 mg/kg, i.p., an [alpha]2-adrenoceptor antagonist), SCH23390 (0.05 mg/kg, s.c., a dopamine D1 receptor ant agonist) or sulpiride (50 mg/kg, i.p., a dopamine D2 receptor antagonist), or vehicle and after 30 min, received FRA (18 g/kg, p.o.) or vehicle injection before being tested 30 min later.
Evidence for the benefit of scorpion antivenom and its efficacy compared with that of commonly used vasodilators, such as prazosin, is scarce.
El prazosin, un antagonista alfa 1 adrenergico y ampliamente utilizado como antihipertensivo, ha mostrado ser eficaz para las pesadillas en el TEPT en reportes de caso y en estudios abiertos, tanto en pacientes civiles como en militares (76-80).
While many of the trials have been open trials, a number of them have been placebo-controlled and crossover, providing compelling evidence for the effectiveness of prazosin. While protocols using up to 20 mg have been described, most studies have shown good results with 2 to 6 mg.
Those [alpha]-blockers that are nonselective to the prostate (doxazosin, prazosin, terazosin) are commonly used in treating hypertension and thus may have potent hypotensive effects, with the longer-acting agents (doxazosin, terazosin) having less of an effect on blood pressure.
Because ALIBRA consists of a single, fixed combination of alprostadil and prazosin HCl, "in office" dosing should not be necessary.
doxazosin mesylate (Cardura) guanfacine HCI (Tenex) hydralazine HCI (Apresoline) labetalol HCI (Normodyne, Trandate) metoprolol tartrate (Lopressor, Toprol XL) nadolol (Corgard) prazosin HCI (Minipress) terazosin HCI (Hytrin) valsartan (Diovan) Psychotherapeutic medications amitriptyline HCI (Elavil) Treats depression.
In any event, muscle relaxants like diazepam or smooth muscle blocking agents like prazosin may offer some symptomatic relief.
Nerve Blockers Generic Name Trade Name rauwolfia derivatives Reserpine guanethidine Ismelin guanadrel Hylorel alpha methyldopa Aldomlet clonidine Catapres guanabenz Wytensin prazosin Minipress terazosin Hytrin Beta Blockers propranolol Inderal metoprolol Lopressor nadolol Corgard atenolol Tenormin timolol Blocadren pindolol Visken acebutolol Sectral labetolol Normodyne or Trandate Blood Vessel Dilators hydralazine, Apresoline minoxidil Loniten(**) Hormone inhibitors captopril Capoten enalapril Vasotec lisinopril Prinivel or Zestril Calcium Channel Blockers nifedipine Procardia verapamil Isoptin or Calan diltiazem Cardizem nicardipine Cardene (*) Many combinations of these drugs are available--usually with a diuretic.
Prior studies evaluating the efficacy of prazosin, an alpha,-adrenergic antagonist, for separate indications of AUD (25,26) and PTSD (27) have demonstrated promising results in reducing alcohol- and PTSD-related outcomes, respectively.