praziquantel


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praziquantel

 [pra″zĭ-kwon´tel]
a broad-spectrum anthelmintic used for treatment of a wide variety of parasitic fluke and tapeworm infections; administered orally.

praziquantel

(prā′zə-kwŏn′tl)
n.
A drug, C19H24N2O2, that kills trematodes and tapeworms parasitic to humans, used especially in the treatment of schistosomiasis.

praziquantel

Biltracide® The antiparasitic of choice for schistosomiasis–S haematobium, S japonicum; flukes or Trematoda–eg, Clonorchis sinensis, Opisthorchis viverrini, Paragonimus buski, Heterophyes heterophyes, Metagonimus yokogawai; tapeworms–Hymenolepsis nana, Taenia solium Side effects Drowsiness, headache, nausea, backache, abdominal discomfort

praziquantel

An ANTHELMINTIC drug used to dispose of tapeworms. The drug is on the WHO official list. A brand name is Cysticide.
References in periodicals archive ?
Praziquantel is the only active ingredient with which all forms of schistosomiasis can be treated.
After praziquantel (Biltracide), the digestion usually improves in several days generally without a dramatic die off.
We therefore advise heightened concurrent surveillance of urogenital and intestinal schistosomiasis, entailing a One-Health approach with molecular vigilance for interspecies interactions along with phenotypic assessments for any altered host pathogenicity or susceptibility to praziquantel treatment.
An extended literature survey revealed that few analytical methods [using high-performance liquid chromatography (HPLC) and HPLC-mass spectrometry] have been reported for estimation of praziquantel. (3-7) To date, one spectrofluorimetric method has been reported for praziquantel quantification in blood plasma and urine.
Among patients with persistent splenomegaly and clinical indicators of Schistosoma infection, such as eosinophilia without any other known cause, clinicians should consider repeating antischistosomal therapy with praziquantel. In addition, because etiology might be multifactorial or patient-specific, clinicians also need to consider further diagnostic testing in cases of persistent splenomegaly for Epstein-Barr virus, autoimmune disorders, or oncologic/hematologic etiologies.
The German company said CENTRAGARD (eprinomectin and praziquantel transdermal solution) is a monthly heartworm disease tropical preventive product for cats.
indicum infestation could be diagnosed by simple laboratory test and could be treated with Fenbendazole and Praziquantel
Nurses from the Department of Health offered a single dose of praziquantel 40 mg per kg of body weight.
They both could be infected through eating raw freshwater crayfish, causing elevated eosinophils in complete blood count and sensitivity to praziquantel. However, it is indiscreet to insist that the patient had paragonimiasis but not clonorchiasis despite the IgG to paragonimiasis was negative while IgG to clonorchiasis was positive.
[5] Pre and Postoperative one-month course of albendazole or praziquantel for two weeks should be considered to sterilise the cyst and decrease the chance of anaphylaxis and to reduce the relapse rate postoperatively.
Currently, the treatment of schistosomiasis relies upon just one drug, praziquantel, which is safe and reasonably effective [6, 7].
The patient was discharged on oral albendazole 400 mg twice daily and oral praziquantel 1800 mg twice weekly.