Total daily insulin doses were lower in pump users, but the prandial
to total insulin ratio was higher.
Addition of prandial
insulin, with corresponding reduction of his basal insulin dose, would lower his PPG, but would have little effect on FPG.
Value of assessing post prandial
and fasting plasma glucose as a surrogate for glycatedhemoglobin in diabetic glycemic control.
After treatment with metformin, mean FBS and TG was significantly decreased; but only mean two hour post prandial
and regular insulin intake were significantly decreased after treatment with acarbose.
Similarly, higher doses of basal NPH plus prandial
regular insulin were prescribed to patients at higher baseline HbA1c levels (>8.
22 patients had Post prandial
level of insulin more than 82 micro IU/ml indicating insulin resistance.
Currently, the investigators are advising patients on pump therapy to use the dual-wave bolus, although novel algorithms to determine prandial
glucose dosing are being refined for high-fat/high-protein diets.
7] Fasting and post prandial
blood sugar was determined using glucometer.
The American Diabetes Association (ADA, 2007) recommends a combination of insulin therapies, including basal insulin, prandial
insulin given with meals and adjusted based on bedside glucose results, and correction or supplemental insulin to lower pre-meal hyperglycemia.
There's always far too much to absorb in far too short a time, but in this issue we distil the Biennale highlights, opening with a snatched prandial
encounter with Rem Koolhaas (page 20)--who was awarded this year's Golden Lion for services to boundary pushing--moving on to look at the best installations and pavilions (page 88), and concluding with a snippet from the archive of Cedric Price (page 98).
Full research and review articles include discussions of insulin resistance and the metabolic syndrome, endothelial dysfunction, adjusting treatment of type-2 diabetes to reflect changes in insulin resistance and secretion and to variations in basal and prandial
glucose along the diabetes continuum, an Asian perspective on the causes of the metabolic syndrome, liver disease, and pathogenetic and therapeutic implications of the link between non-alcoholic fatty liver disease and insulin resistance.
More recent intensive, but flexible, insulin therapy has three components: 1) 24 hour basal, 2) prandial
boluses, and 3) corrective boluses for acute hyperglycaemia (8,9).