is a dopamine agonist that has been approved by the FDA for the treatment of restless legs syndrome.
A 6-month double-blind study of 234 patients using pramipexole
found that 9.
While both iron and pramipexole
are established treatments for restless legs syndrome (RLS), the new study (n = 30) was the first randomized trial to compare them head to head.
For instance, in October 2012, Boehringer-Ingelheim and the Institute of Drug Technology (Farmanguinhos) agreed on a partnership for the local production of Pramipexole
for Parkinson's disease treatment.
Effect of pramipexole
on cutaneous-silent-period parameters in patients with restless legs syndrome.
Thirty-six were on 1 or more concurrent antiparkinsonian medications (carbidopa/levodopa [n=27], pramipexole
[n=3], selegiline [n=2], pramipexole
and selegiline combined [n=4]).
While these medications remain the mainstay of general FS treatment, health care professionals occasionally prescribe several other drugs for the treatment of particular FS-associated conditions: pramipexole
(Mirapex) for restless legs syndrome, gabapentin (Neurontin) for nerve pain and tizanidine hydrochloride (Zanaflex) for muscle spasm.
Symptom improvement, as measured by the International Restless Legs Syndrome Rating Scale of severity, was significantly greater for the pramipexole
group compared to the placebo group.
Eight of the patients were taking a dopamine agonist called pramipexole
and the ninth was on another drug, pergolide.
CANADA--Two dopamine agonists, pramipexole
(Miapex) and ropinirole (Requip), may be responsible for excessive sleepiness in patients with Parkinson's disease.
The three most often used in the United States would be pergolide (Permax), pramipexole
(Mirapex), and ropinirole (Requip).
The dopamine agonist pramipexole
staved off three motor complications longer than levodopa in a double-blind, placebo-controlled trial in patients with early Parkinson's disease, according to Dr.