Results demonstrated that these two heterologous
poxvirus vectors can elicit a broad [CD4.sup.+] and [CD8.sup.+] T-cell responses to the HIV antigens (36).
* The report provides a snapshot of the global therapeutic landscape of
Poxvirus Infections
Poxvirus infection in an American red squirrel (Tamiasciurus hudsonicus) from Northwestern Canada.
Alem disso, os
poxvirus sao resistentes em condicoes ambientais (FLEMMING & MERCER, 2007), e essa caracteristica provavelmente facilitou a infeccao dos animais que utilizavam a mesma pastagem.
Keywords: Molluscum contagiosum,
Poxvirus, Virus diseases.
Previous research had demonstrated that a host-defense protein called protein kinase R (PKR) is a major hurdle to
poxvirus infection.
Scientists have known for many years that the well-studied vaccinia
poxvirus uses two proteins to inhibit the protein kinase R response.
This study ("
Poxvirus infection in a cat with presumptive human transmission," Veterinary Dermatology, 2011) describes a case of cowpox infection in a cat and transmission to a caretaker.
In South America a few studies on the isolation of
poxvirus have been published since the eradication of smallpox.
A phase I-II clinical trial with JX-594, a targeted and GM-CSF-armed oncolytic
poxvirus, by the intratumoral injection in patients with liver tumors [Poster A156].
Poxvirus infections have been present since antiquity with the first evidence of smallpox (the best known
poxvirus) found in Egyptian mummies of the 18th Dynasty (1580-1350 B.C.).
