potassium hydroxide

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Related to potassium hydroxide: sodium hydroxide

po·tas·si·um hy·drox·ide (KOH),

KOH; a strong, penetrating caustic.
Synonym(s): caustic potash

potassium hydroxide (KOH)

a white, soluble, highly caustic compound. Occasionally used in solution as an escharotic for bites of rabid animals, KOH has many laboratory uses as an alkalinizing agent, including the preparation of clinical specimens for examination for fungi under the microscope.

po·tas·si·um hy·drox·ide

(KOH) (pŏ-tasē-ŭm hī-droksīd)
Strong, penetrating caustic.

potassium hydroxide

; KOH topical, strongly alkaline, caustic and keratolytic chemical, liberating hydroxyl (OH-) ions on dissolution in sweat; OH- ions react with and break down side salt linkages of keratin molecules; formulated as 85% pellets; used to achieve local destruction of tissue (e.g. nail matrix) or lesions (e.g. verrucae); see Table 1
Table 1: Caustic agents used in podiatric practice to achieve local tissue destruction
AgentActionSpecial precautionsContraindications
Monochloroacetic acid (crystals or saturated solution) e.g. single VPKeratolytic; hydrolysing agent
Deep penetration
Do not use mask if applying solution
Use a mask if applying crystals
Review in 5-7 days
Neutralize with foot bath ± NaHCO3 or NaCl
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Salicylic acid paste (40-70%) e.g. single VP; plantar hard cornKeratolytic; hydrolysing agentMacerates tissues
Review in 7-14 days
May be used in conjunction with monochloroacetic acid crystals
Neutralize with foot bath ± NaHCO3 or NaCl
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Pyrogallic acid e.g. single VPKeratolytic; oxidizing agentDeep penetration
Review in 3-5 days
Prolonged caustic action
Do not apply more than 3 times sequentially
Stains skin black/brown
Use with great care: may cause deep tissue breakdown
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Trichloroacetic acid (saturated solution; 10% solution) e.g. mosaic VPMild keratolytic
Protein precipitant
Shallow penetration
Neutralize with foot bath ± NaHCO3 or NaCl
Review in 3 weeks
Peripheral vascular disease
Sensory neuropathy
Silver nitrate (70% solution; 75-95% stick) e.g. mosaic VP; as a protective skin application below a maskProtein precipitant
Stains skin black/brown
Maximum effect occurs within 24 hours
Some patients show hypersensitivity to silver nitrate (or experience acute pain)
Neutralize with NaCl foot bath
May be applied in alternate layers with trichloroacetic acid
Peripheral vascular disease
Known sensitivity
Potassium hydroxide (KOH; 85% pellets)Strong keratolyticPotentially deep penetration
Action of KOH stopped by application of 5% acetic acid after macerated coagulum has been removed
Single treatment
Soft-tissue atrophy
Peripheral vascular disease
Sensory neuropathy
Phenol (80% solution or 100% crystal)Protein precipitateAction retarded by flooding with industrial methylated spirit
Skin overspill flooded with glycerine
Review as per postoperative protocol
Peripheral vascular disease (phenol suppresses inflammatory response)

VP, verruca pedis.

References in periodicals archive ?
An open nonrandomized comparative study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum.
Firemen dressed in special protective suits took more than five hours to clear up the drum of potassium hydroxide.
The hydroxyl value represents the number of milligrams of potassium hydroxide needed to neutralize the quantity of acetic-acid consumed in the acetylation of 1g of fat.
A thin layer of liquid potassium hydroxide covering the alloy sends hydrogen to the metal and takes it back in response to changes in voltage.
Examples of bases are ammonium hydroxide (NH4OH), calcium hydroxide (Ca(OH)2), and potassium hydroxide (KOH).
Potassium Hydroxide (Caustic Potash) (CAS 1310-58-3) Market Research Report 2012 presents comprehensive data on potassium hydroxide (caustic potash) markets globally and regionally (Europe, Asia, North America etc.
The plant with its state-of-the-art membrane technology has an annual capacity of 120,000 metric tons of potassium hydroxide solution and 75,000 metric tons of chlorine and hydrogen.
Evonik will take the new plant's potassium hydroxide solution for commercialization and processing at its own site in Lulsdorf, which is where it processes potassium hydroxide solution into various products, including potassium carbonate (potash).
Today, many processors remove the tight-fitting peels of tomatoes using conventional approaches, such as steamheating or jet sprays of heated solutions of sodium hydroxide or potassium hydroxide, followed by a tap water rinse.
Objective To evaluate the efficacy and safety of cryotherapy versus 10% potassium hydroxide (KOH) solution in treating MC.
The process works by placing the corpse into a pressure chamber filled with water and potassium hydroxide that is then pressurised and heated to 180C.
Potassium hydroxide (KOH), which has a current usage of approximately 580,000 tons/year in the United States, is typically produced using chlor-alkali oxidation-reduction reactions that involve hazardous co-products and a byproduct of chloride gas.

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