regulation of microRNA biogenesis in animals," Molecular Cell, vol.
However, it is the posttranscriptional
regulation of the COX-2 gene, which is far more complex, which controls the expression of the protein.
To protect host genome from the deleterious effect in somatic tissues, retrotransposons are recognized by factors like KRAB-ZFPs and KAP1 (TRIM28) and completely silenced through DNA methylation, histone methylation/acetylation, and posttranscriptional
regulation , except in the brains where they provide genetic variations among neurons .
Accumulating evidence attributes a critical role to posttranscriptional
regulation of gene expression, mediated by RNA-binding proteins (RBPs), in human disease and particularly malignant transformation .
Subsequently, it was found that statins stimulate the expression of endothelial NO synthase mainly due to the effect on posttranscriptional
Aside from the aforementioned diverse mechanisms, lncRNAs also participate in the control of the posttranscriptional
events of mRNAs, including the maintenance of RNA stabilization, RNA splicing, translation or degradation, and miRNA generation or regulation (Figure 1(c)) [13-15].
MiRNAs function primarily by binding to 3' untranslated regions (37 UTR) of target miRNAs and usually decrease the expression of target genes at the posttranscriptional
Regulation of TrxR1 Expression under Oxidative Stress.
Our results also indicate that inflammation may suppress the expression of AANAT in the ovine pineal gland both at the transcriptional and posttranscriptional
Transcriptional and posttranscriptional
regulation, signal transduction and cell-type-specific expression.
miR-181b down-regulated the expression of the FAMLF gene at posttranscriptional
and translational levels