postparturient hemoglobinuria

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post·par·tu·ri·ent he·mo·glo·bi·nu·ri·a

a sudden, severe hemolytic disease that appears sporadically in well-nourished dairy cows 2-4 weeks after calving, and usually occurs in stabled animals in the winter and early spring; the cause is not known, although the disease is often associated with hypophosphatemia.


the presence of free hemoglobin in the urine. In true hemoglobinuria the protein has originated from erythrocytes hemolyzed within the vascular system. In false hemoglobinuria it comes from erythrocytes in the urine that have hemolyzed there, leaving red cell envelopes in the urinary sediment. In both forms the urine is colored dark red to almost black.

bacillary hemoglobinuria
is an acute, highly fatal toxemia of cattle and sheep caused by Clostridium haemolyticum (C. novyi type D). It is characterized by hemoglobinuria, jaundice and sudden death with large, usually single infarcts in the liver.
cold hemoglobinuria
intravascular hemolysis occurs in the blood vessels in the intestinal wall immediately after the calf, rarely an adult, has drunk a large amount of very cold water after a period of deprivation. Transient hemoglobinuria may occur. See also cold anemia.
false hemoglobinuria
when lysis of erythrocytes occurs after the urine is passed.
postparturient hemoglobinuria
see postparturient hemoglobinuria.


relates to the dam, in the period immediately after parturition.

postparturient debilitation
the effects of pregnancy, parturition and the onset of heavy lactation especially in animals with multiple offspring, coupled with the high incidence of metabolic diseases and disease of the uterus and the mammary gland at this time can cause serious debilitation which requires intensive management to correct.
postparturient endometritis
inflammation of the endometrium as a result of infection introduced usually at parturition; one of the principal causes of infertility.
postparturient fever
postparturient hemoglobinuria
a disease of high-producing dairy cows in the period of about a month after calving characterized by acute intravascular hemolysis, hemoglobinuria, pallor of mucosae and a heavy mortality rate. Predisposed by a nutritional deficiency of phosphorus or copper.
postparturient hemolytic anemia
see postparturient hemoglobinuria (above).
postparturient hypocalcemia
see milk fever.
postparturient immunosuppression
drain of antibodies in colostrum depletes maternal resources and reduces immune status.
postparturient paresis
see periparturient hypocalcemia.