postanginal sepsis

postanginal sepsis

pharyngitis preceding fever, rigors, cervical adenopathy, internal jugular thrombophlebitis, distant abscesses, and liver involvement, due to Fusobacterium necrophorum.
Synonym(s): Lemmiere syndrome

postanginal sepsis

A rare condition most common in adolescents and young adults, caused by a peripharyngeal abscess 2º to tonsillitis, pharyngitis, or dental procedures; the infection spreads by direct extension, or into the lymphatic or venous channels, causing thrombophlebitis of the internal jugular vein, septic emboli and metastatic abscesses, often to lung Clinical Local, abscess-related Sx–oral and facial edema, hoarseness, dysphagia; lung involvement manifest by high fever, rigors, cough, pleuritic chest pain, hemoptysis, dyspnea Microbiology Fusobacterium necrophorum, peptostreptococci, bacteroides, Eikenella corrodens, S aureus etc Lab PMNs
≥ 30,000/mm3, ↑ LFTs, ↓ platelets, ↑ urinary sediment Management 
High-dose IV antibiotics, covering for anaerobes
Mentioned in ?
References in periodicals archive ?
Lee, "Lemierre's syndrome: two cases of postanginal sepsis," Otolaryngology--Head and Neck Surgery, vol.
LS, also known as necrobacillosis or postanginal sepsis, is a rare life-threatening complication of oropharyngeal infections.
Lemierre syndrome or postanginal sepsis (necrobacillosis) is characterized by septic thrombophlebitis of the internal jugular vein (IJV) with frequent metastatic infections, usually due to anaerobic organisms.
However, it has rarely been reported in the context of postanginal sepsis. Excluding cases related to central venous catheters, 12 cases of septic internal jugular thrombophlebitis related to S.
Broad spectrum antibiotics, including anaerobic coverage should be instituted promptly on suspicion of postanginal sepsis. Antibiotics should then be tailored depending on culture and sensitivity results.
Lemierre's syndrome (postanginal sepsis, necrobacillosis) is characterized by thrombosis of the internal jugular vein that is usually preceded by an infection in the oropharynx or other head and neck site.
Lemierre syndrome: Postanginal sepsis. J Am Board Faro Pract 1995:8:384-91.
* Lemierre syndrome (also known as postanginal sepsis).
Sepsis usually sets in after oropharyngeal symptoms have resolved and hence the term "postanginal sepsis" [7].
When Lemierre first described the syndrome of postanginal sepsis, he noted that most cases developed in the setting of oropharyngeal infection.
Lemierre's syndrome: Two cases of postanginal sepsis. Otolaryngol Head Neck Surg 1995;112:767-72.
Adult respiratory distress syndrome as a complication of postanginal sepsis. Chest 1993;103:1628-9.