post-orgasmic illness syndrome

post-orgasmic illness syndrome

A condition characterised by debilitating symptoms of several hours’ to days’ duration after an orgasm; it is said to affect up to 1% of the general population. This controversial entity has been legitimised by formal recognition by the NIH’s Office of Rare Diseases Research, and National Organization for Rare Disorders (NORD).

Clinical findings
• Menta—Cognitive dysfunction, discomfort, irritability, anxiety, increased susceptibility to cold or other stressors, depression; difficulty in communicating, remembering words, reading and retaining information, concentrating, and socialising.
• Physical—Fatigue, headache, flu-like and allergy-like symptoms (e.g., sneezing, itchy eyes, nasal irritation and muscle pain), sensation of intense warmth.

Imaging
Pituitary changes (e.g., microadenoma).

Lab
Decreased progesterone, testosterone; increased cortisol.

Management
Uncertain; possibly, SSRIs, hormone therapy, hyposensitisation for semen allergies, abstention from sex.
References in periodicals archive ?
Men who get flu-like symptoms after sex are suffering from post-orgasmic illness syndrome, according to a Dutch scientist.
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