positive cooperativity

pos·i·tive co·op·er·a·tiv·i·ty

cooperativity in which successive ligand molecules appear to bind with increasing affinity.
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References in periodicals archive ?
The results obtained from this investigation represents positive cooperativity of comfarol with urease.
Palonosetron is a second generation 5-[HT.sub.3] receptor antagonist superior to other 5-[HT.sub.3] antagonists due to the allosteric binding and positive cooperativity leading to a longer half-life (37 hrs.).
Hill's coefficient for hydrolysis in pH 10.0 and pH 11.0 was >1 indicating positive cooperativity between the interacting sites.
In ligand-receptor binding kinetics, for example, the equation is strictly valid only for simultaneous binding of all ligand molecules; for the more likely sequential or independent binding schemes, it applies only for strong positive cooperativity [5,6].
This remarkably high Hill coefficient may imply multiple HXT binding sites exhibiting positive cooperativity.
When such binding occurs, a conformational change producing positive cooperativity would increase the on-rate of the receptor binding to the fiber.