portal hypertensive gastropathy


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portal hypertensive gastropathy

A vascular gastropathy seen in chronic upper gastrointestinal bleeding in patients with portal hypertension, which is histologically characterised by variable dilation, irregularity and tortuosity of the mucosal and submucosal veins and capillaries, which overlaps with Helicobacter pylori gastritis in patients with concomitant H pylori infection.
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References in periodicals archive ?
Frequency and characteristic features of portal hypertensive gastropathy in patients with viral cirrhosis.
The sample size of 381 was calculated based on a previous study by Kumar et al., who found the prevalence of portal hypertensive gastropathy in patients with cirrhosis to be 55%, with 5% precision and 95% confidence level [19].
They were divided into three groups: (1) the portal hypertensive gastropathy group--203 patients with esophageal varices (EV) and PHG, (2) the esophageal varix group--41 patients with EV but no PHG, and (3) the control group--137 patients with no EV or PHG.
Classification and scoring of portal hypertensive gastropathy were performed according to the Baveno II scoring system; the mild mucosal mosaic pattern was given 1 point, and the severe pattern, 2 points.
The participants were divided into three groups with no significant differences regarding distribution of age, sex, or Child-Pugh class: (1) the portal hypertensive gastropathy group--203 (53.28%) patients with EV and PHG, (2) the esophageal varices group--41 (10.76%) patients with EV but no PHG, and (3) the control group--137 (35.96%) patients with neither EV nor PHG (Table 1).
Portal hypertensive gastropathy (PHG) is a common gastric mucosal anomaly in patients with cirrhosis and portal hypertension [1].
The limitation of this study was the absence of a patient group with portal hypertensive gastropathy and no esophageal varices.
Blood ammonia levels correlate with the presence, severity, and score of portal hypertensive gastropathy in cirrhosis suggesting a causal relationship and encouraging trials of ammonia-lowering treatments for the management of severe PHG with a tendency to bleed.
Saraya, "Factors influencing development of portal hypertensive gastropathy in patients with portal hypertension," Gastroenterology, vol.
Tomikawa, "Pathogenesis of portal hypertensive gastropathy: a clinical and experimental review," Surgery, vol.
Balm, "Acute gastrointestinal bleeding from portal hypertensive gastropathy: prevalence and clinical features," The American Journal of Gastroenterology, vol.
Rossi, "Portal hypertensive gastropathy in cirrhotics without varices: a case-control study," European Journal of Gastroenterology & Hepatology, vol.