porphyrinogens

por·phy·rin·o·gens

(pōr'fi-rin'ō-jenz),
Intermediates in the biosynthesis of heme, as follows: four porphobilinogens condense to form uroporphyrinogens I and III (giving rise to side products uroporphyrins I and III) that are decarboxylated to form coproporphyrinogens I and III (giving rise to side products coproporphyrins I and III); coproporphyrinogen III is oxidized to protoporphyrinogen III (IX), which is then oxidized to form protoporphyrin III (IX) (this last intermediate adds ferrous iron to yield heme); certain porphyrinogens are elevated in certain porphyrias.
Farlex Partner Medical Dictionary © Farlex 2012

por·phy·rin·o·gens

(pōr'fir-in'ō-jenz)
Intermediates in the biosynthesis of heme; certain porphyrinogens are elevated in certain porphyrias.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

por·phy·rin·o·gens

(pōr'fir-in'ō-jenz)
Intermediates in the biosynthesis of heme.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
In EP, a deficient activity of the enzyme uroporphyrinogen III synthase in erythrocyte precursor cells results in overproduction of isomer I porphyrinogens that cannot be used to form heme.
We were interested to find in this study that fecal coproporphyrin was a uniformly better diagnostic marker for VP than protoporphyrin, although the predominant porphyrinogen excreted in bile in individuals with VP is protoporphyrinogen (24).