porcupine skin
ep·i·der·mo·lyt·ic hy·per·ker·a·to·sis
[MIM*144200]characterized by localized lesions, keratosis palmaris and plantaris, and elevated IgE, associated with hyperkeratosis, hypergranulosis, and reticular degeneration in the upper epidermis; autosomal dominant inheritance, caused by mutation in the epidermolytic palmoplantar keratoderma gene (EPPK) on chromosome 17q. Generalized epidermolytic hyperkeratosis is present in bullous congenital ichthyosiform erythroderma.
Synonym(s): porcupine skin
Farlex Partner Medical Dictionary © Farlex 2012
porcupine skin
(1) Ichthyosis hystrix of Curth-Macklin, see there.(2) Ichthyosis hystrix gravior, see there.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.