poractant alfa

[por-ak´tant al´fah]

an extract of porcine lung surfactant administered by instillation via the endotracheal tube in treatment of respiratory distress syndrome of the newborn.

References in periodicals archive ?

Sales of Curosurf[R] (poractant alfa), a pulmonary surfactant, exceeded [euro]200m, growing by 14.4% over 2014 and confirming its global importance as a potentially life-saving drug.

CHIESI FARMACEUTICI

Compliations among premature neonates treated with beractant and poractant alfa. Indian J Pediatr 2010; 77: 751-4.

A randomized, controlled trial of poractant alfa versus beractant in the treatment of preterm infants with respiratory distress syndrome.

The importance of administration of early surfactant and nasal continuous positive airway pressure in newborns with respiratory distress syndrome

27 January 2012 - Cornerstone Therapeutics (NASDAQ:CRTX), a specialty pharmaceutical group focused on products for respiratory conditions, said that a new analysis revealed significant benefits in mortality rate and the need for redosing in the treatment of neonatal respiratory distress syndrome (RDS) with the company's CUROSURF (poractant alfa) Intratracheal Suspension.

Analysis unveils positive effects of Cornerstone's CUROSURF in neonatal RDS

The biological surfactant preparation Curosurf (poractant alfa) was derived from minced porcine lung extracts, and its indications followed similar risk profiles as noted in the biologicals above.

Surfactant: where it comes from and where it's going

EVIDENCE FOR A MORTALITY BENEFIT FOR PORACTANT ALFA?

Is there evidence for a mortality difference between exogenous surfactant preparations in neonatal RDS?

* Poractant alfa (Curosurf) for respiratory distress syndrome.

Pediatric Labeling of Psychiatric Drugs

A randomized, multicenter masked comparison trial of poractant alfa (Curosurf ) versus beractant (Survanta) in the treatment of respiratory distress syndrome in preterm infants.

The use of surfactant in the neonatal period- the known aspects, those still under research and those which need to be investigated further

Examples of natural surfactant include Beractant (Survanta), Poractant Alfa (Curosurf), and Clafactant (Infasurf)