pooled serum


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Related to pooled serum: serum marker

serum

 [se´rum] (pl. serums, se´ra) (L.)
the clear portion of any animal or plant fluid that remains after the solid elements have been separated out. The term usually refers to blood serum, the clear, straw-colored, liquid portion of the plasma that does not contain fibrinogen or blood cells, and remains fluid after clotting of blood. Blood serum from persons or animals whose bodies have built up antibodies is called antiserum or immune serum. Inoculation with such an antiserum provides temporary, or passive, immunity against the disease, and is used when a person has already been exposed to or has contracted the disease. Diseases in which passive immunization is sometimes used include diphtheria, tetanus, botulism, and gas gangrene.
antilymphocyte serum (ALS) antiserum derived from animals that have been immunized against human lymphocytes, a powerful nonspecific immunosuppressive agent that causes destruction of circulating lymphocytes.
antirabies serum antiserum obtained from the blood serum or plasma of animals immunized with rabies vaccine; used for postexposure prophylaxis against rabies if rabies immune globulin is unavailable.
blood grouping s's preparations containing particular antibodies against red cell antigens, used for blood typing. Those most commonly used are the anti-A and anti-B blood grouping serums used to determine ABO blood types and the anti-Rh blood grouping serums (anti-D, anti-C, anti-E, anti-c, and anti-e) used to determine Rh blood types.
serum glutamic-oxaloacetic transaminase (SGOT) see aspartate transaminase.
serum glutamic-pyruvic transaminase (SGPT) see alanine transaminase.
immune serum antiserum.
pooled serum the mixed serum from a number of individuals.
serum sickness a hypersensitivity reaction following the administration of foreign serum or other antigens; it is marked by urticarial rashes, edema, adenitis, joint pains, high fever, and prostration. Reactions to tetanus antitoxin derived from horse serum were especially common but are now rare owing to refinement of the antigenic components.
serum sickness syndrome a serum sickness–like hypersensitivity reaction occurring after the administration of certain drugs. It is marked clinically by low-grade fever, urticaria, facial edema, pain and swelling of the joints, and lymphadenopathy, and occasionally may be associated with neuritis of the brachial plexus, guillain-barré syndrome, periarteritis nodosa, and nephritis.

pooled se·rum

, pooled blood serum
the mixed serum from a number of people.

pooled serum

Serum collected from several donors.
See also: serum
References in periodicals archive ?
To develop an assay specific for proBNP, we tested all NT-proBNP- and BNP-specific MAbs in a sandwich-IFA with recombinant proBNP and pooled serum or plasma from HF patients used as antigens.
Sixty microgram of protein from the pooled serum of 8 patients with MM and eight healthy controls was separated in NuPAGE Novex 4-12% bis-tris gradient gels (Invitrogen) and transferred to a nitrocellulose membranes (Millipore, Billerica, MA, USA) for 30 min using 1 x NuPAGE transfer buffer.
Preincubation of pooled serum with high concentration (1000 [micro]g/mL) of P juliflora revealed significant inhibition of IgE binding to allergenic proteins of A.
The pooled serum osteocalcin and testosterone concentrations were compared between osteoporotic group and non-OP group.
And, just as a spike appears when SPE or CZE in a patient with myeloma is examined, a similar spike appears when the patient's m/z spectrum is compared with that of normal pooled serum.
However, the most recent pooled serum data indicate modest differences by sex as well as ethnicity (Calafat et al.
Pedersen, personal communication, February, 2016, Danish Institute for External Quality Assurance for Laboratories in Health Care (DEKS)]; and, finally, 2 commercial EQA materials from Labquality's EQA scheme Hormones A (2300) survey 6-2013 (EQA1, a liquid pooled serum; EQA2, a human-based lyophilized serum).
Various concentrations of atomic absorption grade cadmium were spiked into the Egyptian pooled serum as well as Intergen's pooled serum (Norcross, GA, USA).
In addition, 3 sera from healthy volunteers (purchased from Trina Bioreactives) were pooled, and 700 [micro]L 25(OH)[D.sub.3] solution at a concentration of 10 [micro]g/mL was spiked into 100 mL pooled serum to prepare a sample containing total 25(OH)D at a concentration of 97.7 ng/mL.
We also analyzed pooled serum samples collected in 1976 from females who resided in zone non-ABR, the "unexposed" zone, to assess concurrent background exposures to other dioxins, furans, and coplanar polychlorinated biphenyls (PCBs).