Polytherapy was required from the beginning in 15% of patients.
Management and treatment with
polytherapy and systemic agents.
Initial treatment with anti-epileptics was successful in controlling the seizures but later on the seizures became intractable even on
polytherapy.
Conclusion: It can be concluded that there is equality in gender distribution among SUDEP patients, that the young adult population has a slightly increased risk for SUDEP, and that the inconsistent use of antiepileptic medicines is a greater risk factor for SUDEP than
polytherapy.
Male and female patients who were aged 18-65 years, taking a first-generation antipsychotic (FGA) or second-generation antipsychotic (SGA) as monotherapy or
polytherapy (combined with other psychotropic medication) for at least 3 months and who met Diagnostic and Statistical Manual of Mental Disorders (4th ed.
There are several case reports of pancreatitis while on VPA as a
polytherapy.
1982) Sodium valproate: monotherapy and
polytherapy.
study in Iran also showed
polytherapy was associated with more ADRs than monotherapy (P = 0.
4%) were on
polytherapy with the following combinations: TPM/VP, LTG/CBZ, CBZ/PB, TPM/CBZ/PHT and VP/CZP.
Pennell noted that the antiseizure medications that the women were taking were typical for women of reproductive age: lamotrigine monotherapy (44%), levetiracetam monotherapy (28%), monotherapy with a strong enzyme-inducing drug (12%), other
polytherapy (10%),
polytherapy with a strong enzyme-inducing drug (6%), other monotherapy (3%), or no antiseizure medication (2%).
Compliance, side effects and complexities of
polytherapy are reasons suggested for these inadequately controlled hypertensives.
It was found that 10 patients whose epileptic seizures still continued were being followed up with
polytherapy.
