During early stages of immune dysfunction, manifestations like Bell's palsy and GBS are common, but during late stages more severe disorders like cryptococcal meningitis, TB meningitis, CMV encephalitis, HIV dementia and the polyradiculopathy
We report a case a demyelinating polyradiculopathy
in a patient with COPD along with a brief review of literature.
Mononeuropathy multiplex (MM), polyradiculopathy
, symptomatic dysautonomia, myopathy, cranial neuropathy and CNS involvement are less common.
Patients, who are mostly middle-age, develop a progressive myelopathy which at the early stage of the disease often mimics a polyradiculopathy
or anterior horn cell disorder.
1994) Further regional variants of acute immune polyneuropathy: bifacial weakness or sixth nerve paresis with paresthesias, lumbar polyradiculopathy
, and ataxia with pharyngealcervical-brachial weakness.
is often at multiple levels, as distinguished from the mono-radicular, well-demarcated pain affecting one of several key dermatomes that's typical in patients with a herniated disc.
is often at multiple levels, as distinguished from the monoradicular, well-demarcated pain affecting one of several key dermatomes that's typical in patients with a herniated disk.
Electrodiagnosis helps to exclude other common causes like polyradiculopathy
or focal mononeuropathies.
Another possibility would be immunologically mediated inflammatory polyradiculopathy
, similar to a regional Guillain-Barre syndrome, which would make more sense immunologically and therefore has slightly more scientific merit; however, neither theory has yet been fully tested.
Central nervous system disease can present with dementia, delirium, seizures, focal neurologic signs, myelopathy, polyradiculopathy
, peripheral neuropathy, and myopathy.
Talpos D, Tien RD, Hesselink JR et al,Magnetic resonance imaging of AIDS related polyradiculopathy
A distinct syndrome of subacute ascending lower extremity weakness with paresthesias and radicular pain, hyporeflexia or areflexia, and urinary retention has been reported and has been termed polyradiculomyelitis (4,6,7), polyradiculopathy
(1,3) or polyradiculomyelopathy (PRAM) (8,9).