polyprotein

polyprotein

(pŏl′ĭ -prō′tēn”) [″ + ″]
A polypeptide that contains the linked transcripts of several proteins. Cleavage of the polypeptide releases the contained protein sequences.

polyprotein

A large gene product that is split into two or more independent proteins.
References in periodicals archive ?
NS5A represents a 447 aa polyprotein containing three distinct domains: 1 (aa 1-213), 2 (250-342), and 3 (356-447) (Figure 1(a)) [28].
IgG, IgM and IgA antibodies against the novel polyprotein in active tuberculosis.
The suggested map of the PRSV polyprotein is outlined in Figure 1.
It possessed a single long ORF of 6684 nucleotides encoding the polyprotein of 2228 aa.
The well known immunosuppressive agent cyclosporin A was originally proposed to suppress HIV-1 replication by interference with the binding of cyclophilin A to the viral Gag polyprotein [50,51].
Segment A encodes a polyprotein that can be cleaved by auto proteolysis to form mature viral proteins VP2, VP3 and VP4 [12].
Its overall genome organization is typical of other coronaviruses, with five major open reading frames (ORFs) encoding the replicase polyprotein, which comprises two-thirds of the genome, and the four major structural proteins.
2D); and clone RSG10-U showed some similarity (37% identities) to a polyprotein (i.e., reverse transcriptase) of Sorghum bicolor (L.) Moench (AAD22158, Fig.
We performed phylogenetic analyses on this virus and all complete rhinovirus polyprotein genes available in the GenBank database.
The M segment comprises a single ORF which encodes a large polyprotein that is cleaved during or after the translation and produces a nonstructural protein (NSm), and two structural surface glycoproteins (Gn and Gc) [2].