polypill


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polypill

A popular term for a drug that combines multiple active pharmaceutical ingredients into a single pill.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

polypill

[″ + L. pilula, a small mass]
1. A pill that contains a mixture of health-promoting ingredients.
2. A panacea.
Medical Dictionary, © 2009 Farlex and Partners

polypill

A proposed medication, to be taken daily, consisting of a STATIN drug to lower blood cholesterol, small doses of three drugs to control blood pressure, 0.8 mg of folic acid to reduce blood homocysteine, and 70 mg of aspirin to reduce the clotting tendency of the blood. The principal targets of this combination are heart attacks and strokes, and the proposers estimate that people who take the polypill will have reduced their risk of these disasters by 80 per cent and will enjoy substantially prolonged lives. The idea has aroused much controversy.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
The results of the clinical trial, published in The Lancet, demonstrate for the first time the effectiveness of a fixed-dose combination pill for preventing cardiovascular disease (heart disease and stroke) and indicate that the benefits of widespread polypill use outweigh any known side effects.
The research claims that, when compared with just receiving lifestyle advice, those who took the polypill reduced their risk of major cardiovascular disease by 34%.
The second group, containing 3,421 people, was given the same advice, but were also required to take a polypill every day.
The polypill led to large reductions in bad cholesterol but had only a slight effect on blood pressure, the study showed.
The polypill in the study contained two common blood pressure drugs, a cholesterol-lowering statin and aspirin, the researchers said.
Gholamreza Roshandel, Ph.D., from Shariati Hospital in Tehran, Iran, and colleagues assessed the effectiveness and safety of a four-component polypill, including aspirin, atorvastatin, hydrochlorothiazide, and enalapril or valsartan, for the prevention of cardiovascular disease in a cohort study including participants of the PolyIran study aged 40 to 75 years from the Golestan province, Iran.
Speaking at the annual meeting of the American College of Cardiology, Ruth Webster, PhD, said that the tested polypill contained half the standard doses of the angiotensin receptor blocker telmisartan (20 mg), the calcium channel blocker amlodipine (2.5 mg), and the diuretic chlorthalidone (12.5 mg).
Summary: TEHRAN (FNA)- Iranian researchers have produced a new type of medicine named 'Polypill' which helps reduction of premature death resulting from heart attack and stroke.
Hopefully, our local drug manufacturers can duplicate what India has done by manufacturing a 'polypill,' a single capsule or tablet containing all these essential drugs.
Srinath Reddy, "Strengths and limitations of using the polypill in cardiovascular prevention," Current Cardiology Reports, vol.