polymorphonuclear leukocyte


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Related to polymorphonuclear leukocyte: Polymorphonuclear cells

leukocyte

 [loo´ko-sīt]
a type of blood cell that lacks hemoglobin and is therefore colorless. Leukocytes are larger in size and fewer in number than erythrocytes; normally the blood has about 8000 of them per mm3. In contrast to erythrocytes, leukocytes can move about under their own power with ameboid movement. Their chief functions are to act as scavengers and to help fight infections. Called also white cell or corpuscle and white blood cell or corpuscle. adj., adj leukocyt´ic.

Leukocytes may be classified in two main groups: the granular leukocytes are the basophils, eosinophils, and neutrophils, and the nongranular leukocytes are the lymphocytes and monocytes. About 63 per cent of all leukocytes are neutrophils; 2.5 per cent are eosinophils; and the remaining types constitute less than 1 per cent each.

Leukocytes are actively engaged in the destruction or neutralization of invading microorganisms and are quickly transported to the vicinity of infection or inflammation, so that they can move through the blood vessel wall to reach the site of injury. For this reason, their life span in the blood is usually very short. When infection is present their numbers are greatly increased and they also become more mobile and move back and forth between the blood, lymph, and tissues. The granulocytes and monocytes are phagocytic, swallowing or ingesting the foreign particles with which they come in contact. During the process of phagocytosis the phagocytes themselves are destroyed. The two types of lymphocytes involved in immunity are B lymphocytes (B cells), which play a role in humoral immunity, and T lymphocytes (T cells), which are important in cell-mediated immunity. Plasma cells are activated B cells that secrete antibodies. Monocytes are also involved in some immune processes.
Types of leukocytes.
agranular l's nongranular leukocyte.
basophilic leukocyte basophil (def. 2).
eosinophilic leukocyte eosinophil.
granular l's leukocytes containing abundant granules in the cytoplasm, including neutrophils, eosinophils, and basophils. Called also granulocyte.
neutrophilic leukocyte neutrophil (def. 2).
nongranular l's leukocytes without specific granules in the cytoplasm, including lymphocytes and monocytes. Called also agranular leukocytes.
polymorphonuclear leukocyte any fully developed, segmented granular leukocyte whose nuclei contain multiple lobes joined by filamentous connections, especially a neutrophil.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pol·y·mor·pho·nu·cle·ar leu·ko·cyte (PMN),

, polynuclear leukocyte
common term for granulocyte or granulocytic leukocyte; the term includes basophilic, eosinophilic, and neutrophilic leukocytes, but is usually used especially with reference to the neutrophilic leukocytes.
Farlex Partner Medical Dictionary © Farlex 2012

pol·y·mor·pho·nu·cle·ar leu·ko·cyte

, polynuclear leukocyte (pol'ē-mōr'fō-nū'klē-ăr lū'kō-sīt, pol'ē-nū'klē-ăr)
Common term for granulocyte or granulocytic leukocyte; includes basophilic, eosinophilic, and neutrophilic leukocytes, but generally used with special reference to the neutrophilic leukocytes.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

pol·y·mor·pho·nu·cle·ar leu·ko·cyte

, polynuclear leukocyte (pol'ē-mōr'fō-nū'klē-ăr lū'kō-sīt, pol'ē-nū'klē-ăr)
Common term for granulocyte or granulocytic leukocyte; includes basophilic, eosinophilic, and neutrophilic leukocytes, but generally used with special reference to the neutrophilic leukocytes.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Granulocytes, identified morphologically as polymorphonuclear leukocytes and immunohistochemically by staining for myeloperoxidase, were absent or were only rarely identified in arterioles involved by a lupus microangiopathy.
Doerschuk, "Effect of zymosan-activated plasma on the deformability of rabbit polymorphonuclear leukocytes," Journal of Applied Physiology, vol.
Effect of urine and urine components on the chemiluminescent response of bacteria-stimulated polymorphonuclear leukocytes. Isr J Med Sci.
Webster GF, Leyden JJ, Tsai CC, Baebni P, McArthur WP (1980) Polymorphonuclear leukocytes lysosomal release in response to Propionibacterium acnes in vitro and its enhancement by sera from patients with inflammatory acne.
Age differences in phagocytosis by polymorphonuclear leukocytes measured by flow cytometry.
ROFA and Ti[O.sub.2] exposure significantly increased leukocyte roiling and adhesion in paired venules, and these cells were positively identified as polymorphonuclear leukocytes (PMNLs).
[4] Nonstandard abbreviations: Ci, cirrhosis; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinase; HCV, hepatitis C virus; CAH, chronic active hepatitis C; MNL, mononuclear leukocyte; PML, polymorphonuclear leukocyte; and RT-PCR, reverse transcription-PCR.
During phagocytosis, the polymorphonuclear leukocytes (PMNs) undergo a striking increase in oxidative metabolism, which is known as the respiratory burst.
ATBF eschars were histologically characterized by inflammation of vessels composed mainly of significantly more polymorphonuclear leukocytes than are found in cases of Mediterranean spotted fever (p<0.05).
The intranasal challenge of OVA resulted in significant increase (p < 0.05) in total cell count, polymorphonuclear leukocytes, differential cell count and platelet count in AR control mice as compared to normal mice.
Histopathology of orbital myositis, also known as "idiopathic inflammatory orbital syndrome", reveals mixed inflammation consisting of fibrosis in various degrees, plasma cells, lymphocytes, macrophages, and polymorphonuclear leukocytes (3).
Previous studies showed that there was the change of cells in sputum of patients with acute asthma exacerbation having RV infection with a significant increase of polymorphonuclear leukocytes and eosinophils [2, 13].

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