They were also told that baby Noah also had polymicrogyria
, meaning Sharon was forced to undergo an emergency cesarean section at 32 weeks, on June 11.
Additionally, an MRI performed in the 31st week of gestation showed encephalomalacic pseudocysts and cortical maldevelopment, which was interpreted as polymicrogyria
. With maternal written informed consent, termination of pregnancy was performed at the 32nd week and sixth day of gestation.
In addition, there is one case of optic nerve hypoplasia combined with polymicrogyria
, which is consistent with the literature .
Patients were identified retrospectively with the following inclusion criteria: (1) pediatric age group (less than or equal to 18 years); (2) diagnosis of polymicrogyria
(PMG) established by MRI; (3) MRI of the brain performed at 3 Tesla, including DTI; (4) language development characterized by a pediatric neurologist.
On cranial magnetic resonance imaging, it was observed that the lateral ventricles were enlarged and polymicrogyria
was present (Figure 1a, b).
Jacob, now nine, was diagnosed with a condition called Partial Trisomy of Chromosome 3 and Polymicrogyria
, and extraordinarily he is the only known sufferer in the world.
The affected hemisphere may show focal or diffuse neuronal migration defects, with areas of polymicrogyria
, pachygyria and heterotopia.
Classic lissencephaly, cobblestone lissencephalies, polymicrogyria
, schizencephaly, and heterotopia have all been described previously in conjunction with anomalies of the corpus callosum [33-35].
The youngster suffers from two rare brain conditions called polymicrogyria
and periventricular nodular heterotopia.
She also has polymicrogyria
which is a condition characterised by abnormal development of the brain before birth.
The boy, who weighed 1,640 g at birth, had a normal karyotype but, at 3 years, brain imaging showed a unilateral polymicrogyria
in the left perisylvian area.
Josef, now three, was born profoundly deaf and with polymicrogyria
affecting the left side of his body with cerebral palsy.