polymerase


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Related to polymerase: RNA polymerase, Taq polymerase

polymerase

 [pah-lim´er-ās]
an enzyme that catalyzes polymerization.
polymerase chain reaction a rapid technique for in vitro amplification of specific DNA or RNA sequences, allowing small quantities of short sequences to be analyzed without cloning.

pol·ym·er·ase

(pol-im'ĕr-ās),
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

/po·lym·er·ase/ (pah-lim´er-ās) an enzyme that catalyzes polymerization.

polymerase

(pə-lĭm′ə-rās′, -rāz′, pŏl′ə-mə-)
n.
Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of polynucleotides of DNA or RNA using an existing strand of DNA or RNA as a template.

polymerase

[pə·lim′ər·ās]
any enzyme that catalyzes polymerization, especially of nucleotides to polynucleotides.

POLA1

A gene on chromosome Xp22.1-p21.3 that encodes the catalytic subunit of DNA polymerase that plays a key role in initiating DNA replication.

pol·ym·er·ase

(pŏ-lim'ĕr-ās)
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

Any enzyme that promotes the linkage of a number of similar or identical chemical subunits into repetitive long-chain molecules (polymers), especially of NUCLEOTIDES to form DNA or RNA. Derivation as in POLYMER with the -ase suffix denoting an enzyme.

polymerase

an enzyme that catalyses the joining of DNA or RNA nucleotides.

polymerase

an enzyme that catalyzes polymerization, particularly of nucleic acids.

polymerase chain reaction
see pcr1.
RNA polymerase
1. an enzyme that synthesizes an RNA copy of the sequence in a limited region of DNA in a process known as DNA transcription. Called also DNA-dependent RNA polymerase.
2. a viral enzyme that synthesizes RNA from an RNA template during viral replication. Called also RNA-dependent RNA polymerase.
RNA-dependent RNA polymerase
see RNA polymerase (above).
Taq polymerase
a DNA polymerase that functions at high temperature; derived from the bacterium Thermus aquaticus and used in the polymerase chain reaction.
References in periodicals archive ?
The unusual origin of the polymerase chain reaction.
says, "If you understand the structure and the mechanism of how RNA polymerase works, it will help yon understand gene regulation," which in turn is "hugely important" to studies of disease.
Prevalence of high risk genital papillomaviruses in the Belgian female population determined by fast multiplex polymerase chain reaction.
The concentration of polymerase was increased to 100 pmol/L with 60-min activation times to compensate for low extension rates.
Only those organisms with active, functional DNA polymerase will yield a positive qPCR following the ETGA assay.
Inhibitors of the polymerase complex would make excellent drug candidates," Stephen White, senior author of the study, said.
Because the isolation of the infectious virus has been unsuccessful, a coupled reverse transcription polymerase chain reaction (RT-PCR) assay has been used both by our group and by McKenna's to detect measles virus RNA.
The Company's pipeline includes FV-100, which is in Phase II clinical development for the treatment of shingles, and INX-189, a nucleotide polymerase inhibitor in development for the treatment of chronic hepatitis C infections.
The method itself is simple and builds on the concepts of nucleic acid structure, strand denaturation and annealing, and DNA polymerase activity as covered in previous installments of this series.
BCX5191 is a novel adenine nucleoside analogue which targets viral RNA polymerase for the potential treatment of hepatitis C.
The research team determined that, in the general population, DNA polymerase eta, an enzyme able to overcome the barriers created by sun damage and ultraviolet rays and continue replicating DNA strands, is structured differently from any other polymerase.
Molecular methods such as real-time polymerase chain reaction (PCR) are more sensitive, detecting <10 genome equivalents per PeR, but PCR can only identify short stretches of poxvirus DNA (1,7).

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