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pertaining to several glands or their secretions.


Denoting several glands or their secretions.


/poly·glan·du·lar/ (-glan´du-lar) pluriglandular.


Denoting several glands or their secretions.
Synonym(s): polyglandular.


pertaining to or affecting several glands.

polyglandular syndrome
immune-mediated disease of more than one organ or endocrine gland in the animal, associated with the presence of autoantibodies. A heritable disorder in humans. In dogs, hypothyroidism and hypoadrenocorticism (Addison's disease) are the most frequent findings. Called also Schmidt's syndrome.

Patient discussion about polyglandular

Q. My boy has diabetes. Recently he was diagnosed with vitiligo. What is it and what can be the reason for this? My boy has diabetes. recently he was diagnosed with vitiligo. Our doctor said that he hopes it not a polyglandular autoimmune syndrome. what is vitiligo and what does this big phrase (polyglandular autoimmune syndrome) mean?

A. Vitiligo is a pigmentation disorder and the major cause of vitiligo is the autoimmunity. Some internal factor cause the destruction of melanocytes cell which produce the melanin a substance responsible for the coloration of skin. this lack of melanin infect results in <a href="http://www.antivitiligo.com/">white patch on skin</a> of hypo pigmentation.
Normally vitiligo is not related with other disease like diabetes. However a little inheritance may include in the occurence of vitiligo.

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References in periodicals archive ?
Betterle C, Lazzarotto F, Presotto F: Autoimmune polyglandular syndrome Type 2: the tip of an iceberg?
The association of chronic mucocutaneous candidiasis, adrenal insufficiency and hypoparathyroidism as components of the autoimmune polyglandular syndrome type 1 (APS-I) or autoimmune polyendocrinopathy candidiasis-ectodermal dystrophy (APECED) is well recognized.
Affecting women more often than men, autoimmune polyglandular syndrome type 2 is a polygenic disorder with onset in childhood or early adulthood; it is characterized by primary adrenal insufficiency or adrenal autoantibodies plus either autoimmune thyroid disease or type 1 diabetes (4).
Although we failed to uncover such an antibody in our patient, similar negative findings have been reported in 73 patients with autoimmune polyglandular syndrome 1 with hypoparathyroidism.
Addisonian crisis precipitated by thyroxine therapy: a complication of type 2 autoimmune polyglandular syndrome.
As many as 40% of patients with idiopathic Addison's disease may exhibit polyglandular endocrine syndromes in which immunologic tissue injuries occur in the thyroid, parathyroid, ovary, pancreas, and skin.
To the Editor: In reading the article "Addisonian Crisis Precipitated by Thyroxine Therapy: A Complication of Type 2 Autoimmune Polyglandular Syndrome," (1) I was reminded of Dr.
VKH syndrome is also associated with other autoimmune disorders, such as autoimmune polyglandular syndrome type 1, (1) hypothyroidism and diabetes mellitus, (2) and Hashimoto's thyroiditis.
The highest risk for polyglandular failure exists in patients with autoimmune adrenal failure and individuals with a family history of polyglandular failure.