polygenic inheritance


Also found in: Encyclopedia.

gal·to·ni·an in·her·i·tance

inheritance in which a measurable phenotype is generated by many loci, the contributions of which are statistically independent, additive, and of about equal value. (The latter are in accordance with the classic central limit therein and justify the use of the multivariate normal distribution in galtonian genetics.)

polygenic inheritance

or quantitative inheritance a genetical system in which a number of genes (more than two) is involved in the control of a character, the character being described as ‘quantitative’ in that it shows a wide range of variability that can be measured (see HERITABILITY). Each ‘polygene’ in the system has only a small effect on the character and cannot be detected individually The expression of a polygenic character is strongly affected by the environment in which the individual exists. For example, human height is affected by diet, human intelligence scores are affected by the social background.
References in periodicals archive ?
Androgenetic alopecia is a type of hair loss that is diffuse, symmetric and progressive affecting both sexes.1 It is an androgen-dependent genetically mediated autosomal dominant disorder with polygenic inheritance.2 It affects both genders but it is more common in men affecting 50%2 as compared to females affecting only 30%.3 Hair thinning begins between the ages of 12-40 years but the frequency increases with age.
The non-allelic effects revealed that this trait has polygenic inheritance but complex.
The class will receive the following laboratory kits: Understanding the Human Genome, DNA Isolation, Eye Color and Polygenic Inheritance, Genetically Modified Food, a Plasmid Simulation, along with a dihybrid cross poster.
There is no evidence suggesting that epignathus caused by environmental agents, mendelian or polygenic inheritance. Sporadic chromosomal changes had been reported, but usually, it has not reported to be associated with epignathus.[sup][5] Chromosomal analysis of this case revealed a normal male karyotype.
According to Peck and Peck (4) many observations have justified polygenic inheritance theory, such as the increased prevalence of dental anomalies and significant differences in gender predilection.
Very little is known about the polygenic inheritance of skin colour.
However the larger estimates of the inflation factors do not have to reflect the population stratification (Yang et al., 2011) under especially polygenic inheritance as was also pointed out by Lee et al.
Congenital abdominal hernia might be due to anatomical variation, polygenic inheritance or infectious diseases (Tyagi and Singh, 2010).
However inheritance of some traits involves complex genetic phenomena such as co- dominance sex-linked genes and polygenic inheritance (Batul 2010).
The involvement of multiple genes (termed polygenic inheritance) has a number of consequences.
Polygenic inheritance refers to conditions determined exclusively by a large number of genes, each with a small effect, acting addictively (i.e.
Researchers also verified that resistance to the pathogen in this population has polygenic inheritance, is conditioned by both additive and dominance genetic effects, and that genotypes with high resistance were rare in the germplasm at that time.