polygenes


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Related to polygenes: Pleiotropic Genes

polygenes

GENES that acting individually have a small effect but that collectively produce a significant phenotypic expression.
References in periodicals archive ?
We provide an evidence that quantitative traits that may be controlled by polygenes and a single gene or mutation may lead to a host of alterations in multiple traits.
In case of the best fit model, the values of second order genetic parameters as well as variation due to major genes ([[sigma].sub.mg.sup.2]) and polygene ([[sigma].sub.pg.sup.2]) for [BC.sub.1], [BC.sub.2] and [F.sub.2] were worked out with the help of proposed formulae (Gai et al., 2003; Zhang, Gai, & Yang, 2003).
(25), that patients with a clinical diagnosis of FH but with no identified mutation (FH/M-) have a significantly higher mean LDL-C-raising SNP score than individuals from the general population (combined sample P < 2.2 X [10.sup.-16]), which suggests that their high plasma LDL-C concentrations are considerably influenced by polygenes. In addition, as previously reported, FH patients who carry an FH-causing mutation (FH/M+) also had higher mean LDL-C SNP scores than the WHII cohort (P = 0.04), which confirms results from Talmud et al.
SOLAR incorporates the information contained in the participants' pedigrees to obtain maximum likelihood estimates for the proportion of unexplained variance due to additive genetic effects from polygenes and the proportion of variance due to unmeasured environmental covariates, measurement error and non-additive genetic effects.
Each phenotype has revealed different patterns of inheritance such as two-allele gene with co-dominant inheritance (7,8), oligogenic or polygenic model (9-11), recessive (12), two locus recessive13, mixed with recessive inheritance (14), and single locus with contribution for polygenes (15) although some studies have failed to demonstrate any autosomal patterns of inheritance (7).
Mapping polygenes. Annual Review of Genetics, New York, v.27, p.205-233, 1993.
For this purpose, no molecular data are used, the aim being to test hypotheses about whether one or more major genes and/or polygenes can account for the observed pattern of familial aggregation, the mode of inheritance, and to estimate the parameters of the best-fitting genetic model [Thomas, 2004].
Afin de bien se situer dans un systeme mondialise, les individus, les collectivites plus polygenes ont besoin de creer des politiques conscientes, des trajectoires fondees sur un desir profond de demarches rationnelles, allant dans le sens de l'auto-determination.
Absence of the third molar is common and is thought to be controlled by polygenes. It has been reported as both autosomal dominant and autosomal recessive.